(Q36473605)

14 August 2017

1 reference

title

Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly (English)

1 reference

14 August 2017

Akhlaq A Farooqui

1

1 reference

14 August 2017

Lloyd A Horrocks

series ordinal

2

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14 August 2017

publication date

1 June 2006

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14 August 2017

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14 August 2017

volume

12

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14 August 2017

issue

3

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14 August 2017

page(s)

245-260

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4-Hydroxynonenal modulates the long-term potentiation induced by L-type Ca2+ channel activation in the rat dentate gyrus in vitro

14 August 2017

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Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus.

21 January 2018

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Cell surface receptors in lysophospholipid signaling

21 January 2018

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4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway

21 January 2018

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Preferential transfer of 2-docosahexaenoyl-1-lysophosphatidylcholine through an in vitro blood-brain barrier over unesterified docosahexaenoic acid.

21 January 2018

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Lysolecithin induces demyelination in vitro in a cerebellar slice culture system.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Amyloid &#946;-Peptide [1-42]-Associated Free Radical-Induced Oxidative Stress And Neurodegeneration in Alzheimers Disease Brain: Mechanisms and Consequences

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Protection by prostaglandins from glutamate toxicity in cortical neurons

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Arachidonic acid increases choline acetyltransferase activity in spinal cord neurons through a protein kinase C-mediated mechanism.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophosphatidylcholine inhibits endothelial cell migration by increasing intracellular calcium and activating calpain

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Regulation of rat hepatocyte protein kinase C ? isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: A signaling pathway to modulate vesicular transport of glycoproteins

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Membrane lipid changes in laminectomized and traumatized cat spinal cord

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

4-hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Inhibition by fatty acids of cyclic AMP-dependent protein kinase activity in brush border membranes isolated from human placental vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858405285923

Activation of ethanolamine phospholipase A2 in Brain during ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Deacylation and reacylation of neural membrane glycerophospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Biochemical aspects of neurodegeneration in human brain: involvement of neural membrane phospholipids and phospholipases A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Omega-3 fatty acids modulate ATPases involved in duodenal Ca absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Docosahexaenoic acid reduces GABA response in substantia nigra neuron of rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Localization and regulation of cytosolic phospholipase A(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Antioxidative effects of docosahexaenoic acid in the cerebrum versus cerebellum and brainstem of aged hypercholesterolemic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Contribution of lipid dynamics on the inhibition of bovine brain synaptosomal Na+-K+-ATPase activity induced by 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Phospholipases as mediators of amyloid beta peptide neurotoxicity: an early event contributing to neurodegeneration characteristic of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Arachidonic acid as a neurotoxic and neurotrophic substance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Glutamate stably enhances the activity of two cytosolic forms of phospholipase A2 in brain cortical cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophosphatidylcholine is a regulator of tyrosine kinase activity and intracellular Ca(2+) level in Jurkat T cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Apoptosis, excitotoxicity, and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Induction of secretory phospholipase A2 in reactive astrocytes in response to transient focal cerebral ischemia in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Arachidonic acid increases inositol phospholipid metabolism and glutamate release in synaptosomes prepared from hippocampal tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Rat brain cortex mitochondria release group II secretory phospholipase A(2) under reduced membrane potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Oxygen free radicals and human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxynonenal impairs the permeability of an in vitro rat blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophosphatidylcholine and 7-oxocholesterol modulate Ca2+ signals and inhibit the phosphorylation of endothelial NO synthase and cytosolic phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Decreased lysophosphatidylcholine/phosphatidylcholine ratio in cerebrospinal fluid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The chronic administration of docosahexaenoic acid reduces the spatial cognitive deficit following transient forebrain ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Effects of 4-hydroxynonenal on adenylate cyclase and 5'-nucleotidase activities in rat liver plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Expression and activities of aldo-keto oxidoreductases in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Regional membrane phospholipid alterations in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

In vivo fatty acid incorporation into brain phospholipids in relation to signal transduction and membrane remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Inhibition of bioenergetics alters intracellular calcium, membrane composition, and fluidity in a neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Physiological mechanisms of lysophosphatidylcholine-induced de-ramification of murine microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Novel omega -- 3-derived local mediators in anti-inflammation and resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Docosahexaenoic acid: membrane properties of a unique fatty acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Cloning and expression of mouse liver phosphatidylserine synthase-1 cDNA. Overexpression in rat hepatoma cells inhibits the CDP-ethanolamine pathway for phosphatidylethanolamine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

On the status of lysolecithin in rat cerebral cortex during ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Deacylation-reacylation of arachidonoyl groups in cerebral phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The expression of myelin protein mRNAs during remyelination of lysolecithin-induced demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Human group IIA secretory phospholipase A2 induces neuronal cell death via apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Secretory phospholipase A2 and phospholipids in neural membranes in an experimental epilepsy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Intracerebroventricular injection of phospholipases A2 inhibitors modulates allodynia after facial carrageenan injection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

The bioactive phospholipid, lysophosphatidylcholine, induces cellular effects via G-protein-dependent activation of adenylyl cyclase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

4-hydroxynonenal and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Immunohistochemical detection of the lipid peroxidation product 4-hydroxynonenal after experimental brain injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

Lysophosphatidylcholine Stimulates Activator Protein 1 and the c-Jun N-terminal Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858405285923

21 January 2018

Identifiers

DOI

10.1177/1073858405285923

1 reference

14 August 2017

1 reference