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Unique MAP Kinase binding sites
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scholarly article
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Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
review article
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Europe PubMed Central
title
Unique MAP Kinase binding sites
(English)
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Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
author
Thomas Moon
object named as
Thomas M Moon
series ordinal
2
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Elizabeth J. Goldsmith
series ordinal
3
object named as
Elizabeth J Goldsmith
1 reference
stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
author name string
Radha Akella
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
language of work or name
English
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publication date
19 November 2007
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Europe PubMed Central
PMCID
2266891
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14 August 2017
published in
Biochimica et Biophysica Acta
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stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
volume
1784
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stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
page(s)
48-55
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stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
issue
1
1 reference
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Europe PubMed Central
PMCID
2266891
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14 August 2017
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Novel strategies for inhibition of the p38 MAPK pathway.
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30 September 2017
Interfering with MAP kinase docking interactions: implications and perspective for the p38 route
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30 September 2017
Mechanisms of MAPK signalling specificity
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30 September 2017
Discovering new MAP kinase inhibitors
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30 September 2017
Crystallization of MAP kinases
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Mitogen activated protein (MAP) kinases: development of ATP and non-ATP dependent inhibitors.
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Mechanisms of drug inhibition of signalling molecules
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30 September 2017
Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3.
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30 September 2017
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases
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Regulation of cellular functions by the ERK5 signalling pathway
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30 September 2017
The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network
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MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits
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Peptide inhibitors of protein kinases-discovery, characterisation and use
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30 September 2017
Structural comparison of p38 inhibitor-protein complexes: a review of recent p38 inhibitors having unique binding interactions
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30 September 2017
Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases
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PubMed Central
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30 September 2017
Targeting the mitogen-activated protein kinase cascade to treat cancer
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30 September 2017
Structural insights into the conformational selectivity of STI-571 and related kinase inhibitors.
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30 September 2017
Targeting JNK3 for the treatment of neurodegenerative disorders
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30 September 2017
Discovery and characterization of a substrate selective p38alpha inhibitor
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30 September 2017
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.
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30 September 2017
Tethering: fragment-based drug discovery
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PubMed Central
reference URL
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30 September 2017
ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts
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PubMed Central
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30 September 2017
Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796)
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30 September 2017
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
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30 September 2017
Targeting JNK for therapeutic benefit: from junk to gold?
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30 September 2017
Molecular recognitions in the MAP kinase cascades
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30 September 2017
Irreversible inhibitors of serine, cysteine, and threonine proteases
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30 September 2017
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
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PubMed Central
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30 September 2017
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)
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PubMed Central
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30 September 2017
Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b
1 reference
stated in
PubMed Central
reference URL
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30 September 2017
Specificity determinants in MAPK signaling to transcription factors
1 reference
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PubMed Central
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30 September 2017
p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines.
1 reference
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PubMed Central
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30 September 2017
MAP kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
30 September 2017
Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Docking domains and substrate-specificity determination for MAP kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
A conserved docking motif in MAP kinases common to substrates, activators and regulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Sulindac inhibits activation of the NF-kappaB pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Structural basis of inhibitor selectivity in MAP kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
The structure of mitogen-activated protein kinase p38 at 2.1-A resolution
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Allosteric enzymes as models for chemomechanical energy transducing assemblies.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
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30 September 2017
Atomic structure of the MAP kinase ERK2 at 2.3 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
30 September 2017
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
30 September 2017
A synthetic inhibitor of the mitogen-activated protein kinase cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
30 September 2017
The transcriptional ETS2 repressor factor associates with active and inactive Erks through distinct FXF motifs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
28 June 2018
A Bipartite Mechanism for ERK2 Recognition by Its Cognate Regulators and Substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
28 June 2018
Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
28 June 2018
Therapeutic promise of JNK ATP-noncompetitive inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
21 September 2018
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
21 September 2018
Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2266891
retrieved
21 September 2018
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18068683
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective targeting of MAPKs to the ETS domain transcription factor SAP-1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18068683
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Docking interactions induce exposure of activation loop in the MAP kinase ERK2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18068683
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18068683
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBAPAP.2007.09.016
1 reference
stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
PMCID
2266891
1 reference
stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
PubMed ID
18068683
1 reference
stated in
Europe PubMed Central
PMCID
2266891
retrieved
14 August 2017
ResearchGate publication ID
5779033
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