(Q36507525)

English

Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity

scientific article published on 15 January 2016

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity (English)

1 reference

Europe PubMed Central

14 August 2017

Louise Deldicque

7

object named as

Louise Deldicque

0 references

3

object named as

Damien Naslain

0 references

1

object named as

Marc Francaux

0 references

author name string

Bénédicte Demeulder

2

1 reference

Europe PubMed Central

14 August 2017

Raphael Fortin

4

1 reference

Europe PubMed Central

14 August 2017

Olivier Lutz

5

1 reference

Europe PubMed Central

14 August 2017

Gilles Caty

6

1 reference

Europe PubMed Central

14 August 2017

publication date

15 January 2016

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

8

1 reference

Europe PubMed Central

14 August 2017

1

1 reference

Europe PubMed Central

14 August 2017

copyright license

Creative Commons Attribution 4.0 International

15 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Aberrant REDD1-mTORC1 responses to insulin in skeletal muscle from Type 2 diabetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Biochemical artifacts in experiments involving repeated biopsies in the same muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

A role for Raptor phosphorylation in the mechanical activation of mTOR signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Targeting anabolic impairment in response to resistance exercise in older adults with mobility impairments: potential mechanisms and rehabilitation approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Interactions between exercise and nutrition to prevent muscle waste during ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Role of PRAS40 in Akt and mTOR signaling in health and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Isoleucine and leucine independently regulate mTOR signaling and protein synthesis in MAC-T cells and bovine mammary tissue slices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

The anabolic response to resistance exercise and a protein-rich meal is not diminished by age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Autophagy: assays and artifacts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Autophagy in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Molecular mechanisms of mTOR-mediated translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Autophagy revisited: a conversation with Christian de Duve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

AMPK phosphorylation of raptor mediates a metabolic checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Maintenance of the musculoskeletal mass by control of protein turnover: the concept of anabolic resistance and its relevance to the transplant recipient.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Insulin resistance of muscle protein metabolism in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Control of protein synthesis by amino acid availability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

30 September 2017

Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

28 June 2018

5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

28 June 2018

Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

28 June 2018

The muscle protein synthetic response to the combined ingestion of protein and carbohydrate is not impaired in healthy older men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Blunting of adaptive responses to resistance exercise training in women over 75y.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Protein anabolic responses to a fed steady state in healthy aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Exercising before protein intake allows for greater use of dietary protein-derived amino acids for de novo muscle protein synthesis in both young and elderly men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Anabolic resistance: the effects of aging, sexual dimorphism, and immobilization on human muscle protein turnover.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Effects of increasing insulin secretion on acute postexercise blood glucose disposal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728660

21 September 2018

Does hypoxia cause sarcopenia? Prevention of hypoxia could reduce sarcopenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

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Proteolytic gene expression differs at rest and after resistance exercise between young and old women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splanchnic and whole-body leucine kinetics in young and elderly men

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

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inferred from PubMed ID database lookup

Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mTOR signalling in young and old human skeletal muscle in response to combined resistance exercise and whey protein ingestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/26784225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU8010047

1 reference

Europe PubMed Central

14 August 2017

release_a7x7xlc6ybdhjdwc72hv3mxyfu

1 reference

https://api.fatcat.wiki/v0/release/a7x7xlc6ybdhjdwc72hv3mxyfu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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