(Q37987085)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Role of PRAS40 in Akt and mTOR signaling in health and disease (English)

1 reference

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23 January 2020

2

1 reference

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23 January 2020

Margriet Ouwens

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Claudia Wiza

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

publication date

21 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Endocrinology and Metabolism

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

E1453-60

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354785%20AND%20SRC:MED&resulttype=core&format=json

Two phases of palmitate-induced insulin resistance in skeletal muscle: impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity.

23 January 2020

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Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis.

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Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients

21 January 2018

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Increased STAT-3 and synchronous activation of Raf-1-MEK-1-MAPK, and phosphatidylinositol 3-Kinase-Akt-mTOR pathways in atypical and anaplastic meningiomas

21 January 2018

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Amino acid signaling in TOR activation

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PIM1-activated PRAS40 regulates radioresistance in non-small cell lung cancer cells through interplay with FOXO3a, 14-3-3 and protein phosphatases.

21 January 2018

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Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

21 January 2018

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An emerging role of mTOR in lipid biosynthesis.

21 January 2018

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PRAS40 deregulates apoptosis in malignant melanoma

21 January 2018

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21 January 2018

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Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats

21 January 2018

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PRAS40: target or modulator of mTORC1 signalling and insulin action?

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Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.

21 January 2018

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The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1

21 January 2018

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Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

21 January 2018

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Tissue-specific coupling between insulin/IGF and TORC1 signaling via PRAS40 in Drosophila

21 January 2018

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The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling

21 January 2018

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21 January 2018

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21 January 2018

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PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Preclinical pharmacology, antitumor activity, and development of pharmacodynamic markers for the novel, potent AKT inhibitor CCT128930.

21 January 2018

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21 January 2018

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21 January 2018

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

21 January 2018

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21 January 2018

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21 January 2018

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