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Treatment of infant leukemias: challenge and promise
scientific article published on January 2013
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scholarly article
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Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
title
Treatment of infant leukemias: challenge and promise
(English)
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Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
author name string
Patrick Brown
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
publication date
1 January 2013
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Europe PubMed Central
PMCID
4729208
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14 August 2017
published in
Hematology / the Education Program of the American Society of Hematology
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Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
volume
2013
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Europe PubMed Central
PMCID
4729208
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14 August 2017
page(s)
596-600
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Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
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MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism
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Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia
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Modifications to induction therapy decrease risk of early death in infants with acute lymphoblastic leukemia treated on Children's Oncology Group P9407
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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
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DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis
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Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.
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Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
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Treating childhood acute lymphoblastic leukemia without cranial irradiation
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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
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30 September 2017
Combinations of the FLT3 inhibitor CEP-701 and chemotherapy synergistically kill infant and childhood MLL-rearranged ALL cells in a sequence-dependent manner
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30 September 2017
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30 September 2017
Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia
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30 September 2017
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FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
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30 September 2017
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
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30 September 2017
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia
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PubMed Central
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30 September 2017
Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia
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PubMed Central
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30 September 2017
Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age.
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PubMed Central
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30 September 2017
The role of immunophenotype in acute lymphoblastic leukemia of infant age.
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30 September 2017
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants
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28 June 2018
Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729208
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21 September 2018
Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia
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PubMed Central
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21 September 2018
Outcome of recurrent or refractory acute lymphoblastic leukemia in infants with MLL gene rearrangements: A report from the Japan Infant Leukemia Study Group.
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21 September 2018
Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.
1 reference
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PubMed Central
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21 September 2018
Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group.
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21 September 2018
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
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21 September 2018
Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage
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21 September 2018
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729208
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21 September 2018
In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype
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21 September 2018
Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification
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21 September 2018
Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children
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21 September 2018
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities
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21 September 2018
Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion.
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21 September 2018
Late effects in survivors of infant leukemia.
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21 September 2018
Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale
1 reference
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https://pubmed.ncbi.nlm.nih.gov/24319237
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report
1 reference
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https://pubmed.ncbi.nlm.nih.gov/24319237
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based on heuristic
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Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/24319237
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/ASHEDUCATION-2013.1.596
1 reference
stated in
Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
PMCID
4729208
1 reference
stated in
Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
PubMed ID
24319237
1 reference
stated in
Europe PubMed Central
PMCID
4729208
retrieved
14 August 2017
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