(Q36519025)

14 August 2017

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title

Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis (English)

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14 August 2017

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hepatocellular carcinoma

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Kremsdorf D

1

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14 August 2017

Soussan P

series ordinal

2

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14 August 2017

Paterlini-Brechot P

series ordinal

3

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14 August 2017

Brechot C

series ordinal

4

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14 August 2017

language of work or name

English

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publication date

1 June 2006

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14 August 2017

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14 August 2017

volume

25

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14 August 2017

issue

27

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14 August 2017

page(s)

3823-3833

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209559

14 August 2017

exact match

0 references

cites work

Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatocellular carcinoma: an overview

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Molecular cloning of a rat chromosome putative recombinogenic sequence homologous to the hepatitis B virus encapsidation signal

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The enigmatic X gene of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Calcium signaling by HBx protein in hepatitis B virus DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely "occult"?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Activation of the N-myc2 oncogene by woodchuck hepatitis virus integration in the linked downstream b3n locus in woodchuck hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The win locus involved in activation of the distal N-myc2 gene upon WHV integration in woodchuck liver tumors harbors S/MAR elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Impaired function of hepatic natural killer cells from murine chronic HBsAg carriers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The hepatitis B virus X gene induces p53-mediated programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Calcium ions affect the hepatitis B virus core assembly.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in hepatitis B virus X antigen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus preC mutants in human hepatocellular carcinoma tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The up-regulation of proteasome subunits and lysosomal proteases in hepatocellular carcinomas of the HBx gene knockin transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Identification of a pre-S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Prevalence and significance of hepatitis B virus (HBV) pre-S mutants in serum and liver at different replicative stages of chronic HBV infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Inhibition of hepatitis B virus surface antigen gene expression in carcinogen-induced liver tumors from transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The oncogenic potential of herpes simplex viruses: evidence for a ‘hit-and-run’ mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Loss and acquisition of duck hepatitis B virus integrations in lineages of LMH-D2 chicken hepatoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Cytokine-mediated control of viral infections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Mx proteins: mediators of innate resistance to RNA viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Intracellular localization of the hepatitis B virus HBx protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Frequent detection of antibodies to hepatitis B virus x-protein in acute, chronic and resolved infections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hit-and-run mechanism of HBV-mediated progression to hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Understanding the hypercarcinogenic state in chronic hepatitis: a clue to the prevention of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Advances in chronic viral hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

High prevalence of hepatitis B virus pre-s mutant in countries where it is endemic and its relationship with genotype and chronicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Detection of the hepatitis B virus X protein (HBx) antigen and anti-HBx antibodies in cases of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

HLA-A2 1 restricted peptides from the HBx antigen induce specific CTL responses in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

c-Fos is a mediator of the c-myc-induced apoptotic signaling in serum-deprived hepatoma cells via the p38 mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus core protein stimulates the proteasome-mediated degradation of viral X protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Src kinases involved in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Early hepatocellular carcinoma and dysplastic nodules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Large liver cell dysplasia in hepatitis B virus x transgenic mouse liver and human chronic hepatitis B virus-infected liver.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Cytokines in viral hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Specific mutations of hepatitis B virus in plasma predict liver cancer development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatocellular carcinoma in a hepatitis B 'x' transgenic mouse model: A sequential pathological evaluation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus transgenic mouse model of chronic liver disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The inhibition of apoptosis of hepatoma cells induced by HBx is mediated by up-regulation of survivin expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Biological impacts of "hot-spot" mutations of hepatitis B virus X proteins are genotype B and C differentiated

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Replication of hepatitis B virus in a hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Sequences of hepatitis B virus DNA in the serum and liver of patients with acute benign and fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

In vivo hierarchy of immunodominant and subdominant HLA-A*0201-restricted T-cell epitopes of HBx antigen of hepatitis B virus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Expression of hepatitis B virus X oncoprotein inhibits transcription-coupled nucleotide excision repair in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Epidemiology and natural history of hepatitis B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus DNA replication is coordinated by core protein serine phosphorylation and HBx expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Precore/core mutations of hepatitis B virus in hepatocellular carcinomas developed on noncirrhotic livers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Pathogenesis of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Accreditation and diversity in engineering education

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Immune pathogenesis of hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg but positive for anti-HBs and anti-HBc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus genotypes and hepatocellular carcinoma in Japan

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Clonal analysis of macronodules in cirrhosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Persistence of Hepatitis B and Hepatitis C Viral Genomes in Primary Liver Cancers from HBsAg-Negative Patients: A Study of a Low-endemic Area

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Detection of hepatitis B virus DNA in mononuclear blood cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Genotypic variability of hepatitis viruses associated with chronic infection and the development of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Interrupted replication of hepatitis B virus in liver tissue of HBsAg carriers with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Virus replication and virion export in X-deficient hepatitis B virus transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Inhibition of hepatitis B virus replication by interferon requires proteasome activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatocellular carcinoma: molecular pathways and new therapeutic targets.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Inhibition of interferon-inducible MxA protein expression by hepatitis B virus capsid protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

An association between viral genes and human oncogenic alterations: the adenovirus E1A induces the Ewing tumor fusion transcript EWS-FLI1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Expression of fas ligand in human hepatoma cell lines: role of hepatitis-B virus X (HBX) in induction of Fas ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

UVDDB p127-binding modulates activities and intracellular distribution of hepatitis B virus X protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

"Hit and run" transformation of mouse C127 cells by bovine papillomavirus type 4: the viral DNA is required for the initiation but not for maintenance of the transformed phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The expression of hepatitis B spliced protein (HBSP) encoded by a spliced hepatitis B virus RNA is associated with viral replication and liver fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Possible contribution to hepatocarcinogenesis of X transcript of hepatitis B virus in Japanese patients with hepatitis C virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Alteration of gene expression in human hepatocellular carcinoma with integrated hepatitis B virus DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Defective hepatitis B virus particles are generated by packaging and reverse transcription of spliced viral RNAs in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Enhancement of hepatitis B virus replication by its X protein in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Identification and characterization of a prevalent hepatitis B virus X protein mutant in Taiwanese patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Hepatitis B virus X protein promotes cell migration by inducing matrix metalloproteinase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Sequence of hepatitis B virus DNA incorporated into the genome of a human hepatoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209559

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209559

1 reference

Dimensions Publication ID

14 August 2017

1028156423

0 references

1 reference