(Q36544899)

14 August 2017

Insights into the role of heme in the mechanism of action of antimalarials (English)

1 reference

14 August 2017

0 references

Heinrich C Hoppe

7

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author name string

Jill M Combrinck

1

1 reference

14 August 2017

Tebogo E Mabotha

2

1 reference

14 August 2017

Kanyile K Ncokazi

3

1 reference

14 August 2017

Melvin A Ambele

4

1 reference

14 August 2017

Dale Taylor

5

1 reference

14 August 2017

Peter J Smith

6

1 reference

14 August 2017

Timothy J Egan

8

1 reference

14 August 2017

11 October 2012

1 reference

14 August 2017

1 reference

14 August 2017

8

1 reference

14 August 2017

1

1 reference

14 August 2017

133-137

1 reference

Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

The Plasmodium falciparum-infected red blood cell

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates β-hematin formation with an unusually low activation energy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Chemical genetics of Plasmodium falciparum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Thousands of chemical starting points for antimalarial lead identification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Colorimetric high-throughput screen for detection of heme crystallization inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Artemisinins target the SERCA of Plasmodium falciparum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Artemisinin Antimalarials Do Not Inhibit Hemozoin Formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

The structure of malaria pigment beta-haematin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

On the molecular mechanism of chloroquine's antimalarial action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Human malaria parasites in continuous culture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

A colorimetric high-throughput beta-hematin inhibition screening assay for use in the search for antimalarial compounds

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Fate of haem iron in the malaria parasite Plasmodium falciparum

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment).

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548943

Hemin-induced lipid membrane disorder and increased permeability: a molecular model for the mechanism of cell lysis

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23043646

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23043646

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB300454T

1 reference

release_2d356yqoercmjh2msww545erla

14 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2d356yqoercmjh2msww545erla

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 August 2017

PubMed publication ID

23043646

1 reference