(Q36544972)

14 August 2017

1 reference

title

Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations (English)

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14 August 2017

Strolin Benedetti M

1

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14 August 2017

Whomsley R

series ordinal

2

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14 August 2017

Baltes EL

series ordinal

3

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14 August 2017

language of work or name

English

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publication date

1 October 2005

1 reference

Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

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14 August 2017

volume

1

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14 August 2017

issue

3

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14 August 2017

page(s)

447-471

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Developmental changes in pharmacokinetics and pharmacodynamics of warfarin enantiomers in Japanese children.

14 August 2017

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Absorption characteristics of once-a-day slow-release theophylline preparation in children with asthma.

21 January 2018

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Influence of food on the absorption rate and bioavailability of a sustained release theophylline preparation.

21 January 2018

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Erratic absorption of theophylline from slow-release products in children

21 January 2018

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Effects of food on the absorption of theophylline in children.

21 January 2018

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Pharmacokinetics of a sustained-release theophylline preparation in infants and preschool children with asthma.

21 January 2018

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Pharmacokinetics in children

21 January 2018

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Developmental pharmacology--drug disposition, action, and therapy in infants and children

21 January 2018

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Intramuscular injection of drugs

21 January 2018

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Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part I).

21 January 2018

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Plasma-diazepam in infants after rectal administration in solution and by suppository.

21 January 2018

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Pharmacokinetic Studies with a Long-Acting sulfnamide in Subjects of Different Ages: A Modern Approach to Drug Dosage Problems in Developmental Pharmacology

21 January 2018

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Adverse central nervous system effects of older antihistamines in children.

21 January 2018

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Size, myths and the clinical pharmacokinetics of analgesia in paediatric patients.

21 January 2018

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Pharmacokinetic and pharmacodynamic data collection in children and neonates. A quiet frontier

21 January 2018

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Clinical pharmacokinetics in newborns and infants. Age-related differences and therapeutic implications

21 January 2018

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Altered plasma albumin in the newborn infant

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Studies in kernicterus. I. The protein binding of bilirubin

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Pharmacokinetic aspects of theophylline in premature newborns

21 January 2018

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Differences in pharmacokinetics between children and adults--II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental Aspects of Drug Conjugation, with Special Reference to Glucuronidation

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Metabolism of theophylline to caffeine in premature newborn infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental aspects of theophylline metabolism in premature infants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Valproic acid hepatic fatalities: a retrospective review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Valproate-associated hepatotoxicity and its biochemical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Distribution of UDP-glucuronyltransferase in different human foetal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Expression of CYP2D6 in developing human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

A review of developmental aspects of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Delayed ontogenesis of CYP1A2 in the human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

The role of cytochrome P450 in developmental pharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Theophylline toxicokinetics in premature newborns

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental expression of cytochrome P450 enzymes in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Cytochrome P-450 expression in sudden infant death syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental expression of human hepatic CYP2C9 and CYP2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Expression of biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Gender effects in pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Population pharmacokinetic analysis of netilmicin in neonates and infants with use of a nonparametric method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Immunocytochemical localization of monoamine oxidases A and B in human peripheral tissues and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Stereoselectivity of idarubicin reduction in various animal species and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Interindividual variation in the enzymatic 15-keto-reduction of 13,14-dihydro-15-keto-prostaglandin E1 in human liver and in human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Xenobiotic carbonyl reduction and physiological steroid oxidoreduction. The pluripotency of several hydroxysteroid dehydrogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Perinatal development of human blood esterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

CONJUGATION REACTIONS IN THE NEWBORN INFANT: THE METABOLISM OF PARA-AMINOBENZOIC ACID

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

N-acetyltransferase 2 genotyping: an accurate and feasible approach for simultaneous detection of the most common NAT2 alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Pharmacogenetics in pediatrics. Implications for practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Development of multiple activities of UDP-glucuronyltransferase in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Insufficient glucuronide formation in the newborn and its relationship to the pathogenesis of icterus neonatorum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Morphine metabolism in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Human adult and foetal liver sulphotransferases: inhibition by mefenamic acid and salicylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Human sulfotransferase SULT1C1: cDNA cloning, tissue-specific expression, and chromosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Clinical pharmacokinetics of the salicylates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

A recombinant model for assessing the role of GSTM1 in styrene-7,8-oxide toxicity and mutagenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

[Intestinal flora in the neonate: impact on morbidity and therapeutic perspectives]

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Metabolism of drugs and other xenobiotics in the gut lumen and wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Allergy development and the intestinal microflora during the first year of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Perinatal Renal Pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

RENAL EXTRACTION OF PARA-AMINOHIPPURATE IN INFANTS AND CHILDREN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

12-hour versus 24-hour creatinine clearance in critically ill pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Intra-individual variation of cystatin C and creatinine in pediatric solid organ transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Clinical pharmacokinetics of levetiracetam

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

A pharmacokinetic evaluation of the second-generation H1-receptor antagonist cetirizine in very young children

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Relationships between plasma theophylline clearance, liver volume and body weight in children and adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Pharmacokinetics of Methicillin in Patients with Cystic Fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Correlation of lamotrigine concentrations between serum and saliva

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Multidrug resistance: molecular mechanisms and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Cellular and molecular aspects of drug transport in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Multiple drug resistance mediated by P-glycoprotein is not a major factor in a slow response to therapy in childhood ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Ontogeny of P-glycoprotein in mouse intestine, liver, and kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

A size standard for pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Common errors of drug administration in infants: causes and avoidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Scaling for size: some implications for paediatric anaesthesia dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

The effects of acute falciparum malaria on the disposition of caffeine and the comparison of saliva and plasma-derived pharmacokinetic parameters in adult Nigerians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Accelerator mass spectrometry in pharmaceutical research and development--a new ultrasensitive analytical method for isotope measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

Ontogenesis of monoamine oxidase-A and -B in the human brain frontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.447

21 January 2018

Identifiers

DOI

10.1517/17425255.1.3.447

1 reference

14 August 2017

1 reference