(Q36548335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Xu Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Amanda Engstrom

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Elizabeth L Zoeller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

John R Shanks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Xing Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Margaret A Johns

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Paula M Vertino

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Haian Fu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Xiaodong Cheng

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

8 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 March 2020

published in

1 reference

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2 March 2020

volume

291

1 reference

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2 March 2020

issue

6

1 reference

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2 March 2020

page(s)

2631-2646

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

Assessing and maximizing data quality in macromolecular crystallography

2 March 2020

cites work

1 reference

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The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential

30 September 2017

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A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC.

30 September 2017

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Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases

30 September 2017

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KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease

30 September 2017

1 reference

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Prolonged and tunable residence time using reversible covalent kinase inhibitors

30 September 2017

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EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity

30 September 2017

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The Phyre2 web portal for protein modeling, prediction and analysis

30 September 2017

1 reference

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Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism

30 September 2017

1 reference

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Structural definitions of Jumonji family demethylase selectivity

30 September 2017

1 reference

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JARID1B is a luminal lineage-driving oncogene in breast cancer

30 September 2017

1 reference

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Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

30 September 2017

1 reference

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Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma

30 September 2017

1 reference

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KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation

30 September 2017

1 reference

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Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA

30 September 2017

1 reference

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Targeting H3K4 trimethylation in Huntington disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

30 September 2017

1 reference

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Targeting epigenetic readers in cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Cancer epigenetics: from mechanism to therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Linking Crystallographic Model and Data Quality

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Epigenetic protein families: a new frontier for drug discovery

30 September 2017

1 reference

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Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

30 September 2017

1 reference

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An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases

30 September 2017

1 reference

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Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

30 September 2017

1 reference

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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

30 September 2017

1 reference

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Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

30 September 2017

1 reference

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The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

30 September 2017

1 reference

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Romidepsin: a novel histone deacetylase inhibitor for cancer

30 September 2017

1 reference

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PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

30 September 2017

1 reference

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Features and development of Coot

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Chemical phylogenetics of histone deacetylases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

PHENIX: a comprehensive Python-based system for macromolecular structure solution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer

30 September 2017

1 reference

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Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation

30 September 2017

1 reference

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Functional analysis of the transcription repressor PLU-1/JARID1B.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The landscape of histone modifications across 1% of the human genome in five human cell lines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The epigenomics of cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Epigenetic therapy of cancer: past, present and future

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Binding of pRB to the PHD protein RBP2 promotes cellular differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Coot: model-building tools for molecular graphics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Multiparametric scaling of diffraction intensities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

PHENIX: building new software for automated crystallographic structure determination

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

30 September 2017

https://api.crossref.org/works/10.1074%2FJBC.M115.698449

A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Inhibition of demethylases by GSK-J1/J4.

28 June 2018

1 reference

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Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742734

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.698449

Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.698449

The KDM5 family of histone demethylases as targets in oncology drug discovery

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26645689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular biology. Genetic events that shape the cancer epigenome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26645689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M115.698449

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26645689%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

26645689

1 reference