(Q36556326)

English

Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

scientific article published on 21 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

based on heuristic

inferred from title

Michael P. Lisanti

10

object named as

Michael P Lisanti

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

Federica Sotgia

1

object named as

Federica Sotgia

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

Diana Whitaker-Menezes

2

object named as

Diana Whitaker-Menezes

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

Ubaldo E Martinez-Outschoorn

3

object named as

Ubaldo E Martinez-Outschoorn

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

9

object named as

Anthony Howell

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Aristotelis Tsirigos

5

object named as

Aristotelis Tsirigos

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

8

object named as

James Hulit

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

7

object named as

Sharon Sneddon

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Ahmed F Salem

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Rebecca Lamb

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

publication date

21 November 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

4390-4401

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Ketone body utilization drives tumor growth and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

1 reference

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High expression of GOLPH3 in esophageal squamous cell carcinoma correlates with poor prognosis

1 reference

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Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1α, autophagy and ketone body production

1 reference

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30 September 2017

Mitochondria and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis

1 reference

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Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

1 reference

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GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer

1 reference

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Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth

1 reference

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Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.

1 reference

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Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

1 reference

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CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.

1 reference

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30 September 2017

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue

1 reference

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30 September 2017

Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers

1 reference

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30 September 2017

Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers

1 reference

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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

1 reference

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HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

1 reference

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Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

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Stromal cell expression of caveolin-1 predicts outcome in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552922

30 September 2017

Increased expression of Golgi phosphoprotein-3 is associated with tumor aggressiveness and poor prognosis of prostate cancer

1 reference

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TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome.

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21 September 2018

Overexpression of Golgi phosphoprotein-3 (GOLPH3) in glioblastoma multiforme is associated with worse prognosis.

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21 September 2018

Stromal caveolin-1 expression in breast carcinoma. Correlation with early tumor recurrence and clinical outcome

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21 September 2018

Prognostic significance of tumor/stromal caveolin-1 expression in breast cancer patients

1 reference

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21 September 2018

High TIMM17A expression is associated with adverse pathological and clinical outcomes in human breast cancer

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Loss of stromal caveolin-1 expression in malignant melanoma metastases predicts poor survival

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23172368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Power cut: inhibiting mitochondrial translation to target leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23172368

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inferred from PubMed ID database lookup

Therapeutic potential of mitochondrial translation inhibition for treatment of acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23172368

12 December 2020

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inferred from PubMed ID database lookup

Power surge: supporting cells "fuel" cancer cell mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/23172368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CC.22777

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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