(Q36563528)

14 August 2017

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title

Transforming growth factor-beta and T-cell-mediated immunoregulation in the control of autoimmune diabetes (English)

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14 August 2017

5

Lucienne Chatenoud

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author name string

Sylvaine You

1

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14 August 2017

Nathalie Thieblemont

2

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14 August 2017

Marie-Alexandra Alyanakian

3

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14 August 2017

Jean-François Bach

4

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14 August 2017

publication date

1 August 2006

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14 August 2017

published in

Immunological Reviews

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14 August 2017

volume

212

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14 August 2017

page(s)

185-202

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Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats

14 August 2017

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

21 January 2018

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Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.

21 January 2018

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Tolerance to islet autoantigens in type 1 diabetes

21 January 2018

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Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

21 January 2018

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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

21 January 2018

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Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

21 January 2018

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IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse.

21 January 2018

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Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide

21 January 2018

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Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

21 January 2018

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TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype

21 January 2018

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CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

21 January 2018

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Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice

21 January 2018

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

21 January 2018

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Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

21 January 2018

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Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens

21 January 2018

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Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

21 January 2018

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Diabetes trends in the USA.

21 January 2018

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Immunomodulation with human recombinant autoantigens

21 January 2018

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Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

21 January 2018

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Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial

21 January 2018

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Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies

21 January 2018

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Regulating the immune response to transplants. a role for CD4+ regulatory cells?

21 January 2018

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Mechanisms of transplant tolerance induction using costimulatory blockade

21 January 2018

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CD40/CD154 interactions at the interface of tolerance and immunity

21 January 2018

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Immunotherapy as a means to induce transplantation tolerance

21 January 2018

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

21 January 2018

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CD3-specific antibody-induced active tolerance: from bench to bedside

21 January 2018

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Long-term abrogation of autoimmune diabetes in nonobese diabetic mice by immunotherapy with anti-lymphocyte serum

21 January 2018

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

21 January 2018

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

21 January 2018

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Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis

21 January 2018

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TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

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Regulatory T cells under scrutiny

21 January 2018

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Natural versus adaptive regulatory T cells

21 January 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

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Control of autoimmunity by naturally arising regulatory CD4+ T cells

21 January 2018

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Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 January 2018

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

21 January 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

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TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors

21 January 2018

1 reference

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Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

21 January 2018

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Human CD4+CD25+ regulatory T cells

21 January 2018

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Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells

21 January 2018

1 reference

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 January 2018

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

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Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25- T cells

21 January 2018

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Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus

21 January 2018

1 reference

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

21 January 2018

1 reference

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The effect of infections on susceptibility to autoimmune and allergic diseases

21 January 2018

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On the mechanisms of the protective effect of infections on type 1 diabetes

21 January 2018

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Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence

21 January 2018

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Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection

21 January 2018

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Persistent MHV (mouse hepatitis virus) infection reduces the incidence of diabetes mellitus in non-obese diabetic mice

21 January 2018

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Effect of adjuvant therapy on development of diabetes in mouse and man.

21 January 2018

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Immunostimulation with OM-85 in children with recurrent infections of the upper respiratory tract: a double-blind, placebo-controlled multicenter study

21 January 2018

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Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non-obese diabetic mice

21 January 2018

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10.1111/J.0105-2896.2006.00410.X

21 January 2018

Identifiers

DOI

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14 August 2017

1 reference