(Q36583034)

English

Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling

scientific article published on 16 February 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

author name string

Feng Liu

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Wen Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Fusheng Yang

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Tingting Feng

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Meng Zhou

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Yuan Yu

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Xiuping Yu

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Weiming Zhao

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Fan Yi

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Wei Tang

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Yi Lu

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

16 February 2016

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Europe PubMed Central

PMC publication ID

15 August 2017

Scientific Reports

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Europe PubMed Central

PMC publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

21260

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

copyright license

Creative Commons Attribution 4.0 International

16 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep21260

0 references

Mechanisms of hepatocellular carcinoma and challenges and opportunities for molecular targeted therapy

1 reference

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Global cancer statistics, 2012

1 reference

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Progranulin protects against renal ischemia/reperfusion injury in mice

1 reference

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IL-6 and related cytokines as the critical lynchpins between inflammation and cancer

1 reference

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Combination of cetuximab and rapamycin enhances the therapeutic efficacy in hepatocellular carcinoma.

1 reference

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Targeting the mTOR pathway in hepatocellular carcinoma: current state and future trends

1 reference

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The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.

1 reference

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mTor as a potential target for the prevention and treatment of hepatocellular carcinoma

1 reference

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Interleukin-6 signaling pathway in targeted therapy for cancer

1 reference

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Plasticity and cross-talk of interleukin 6-type cytokines

1 reference

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Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

1 reference

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Hepatocellular carcinoma

1 reference

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Applications of post-translational modifications of FoxO family proteins in biological functions

1 reference

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The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

1 reference

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Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance

1 reference

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Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.

1 reference

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The granulin gene family: from cancer to dementia

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Effective inhibition of xenografts of hepatocellular carcinoma (HepG2) by rapamycin and bevacizumab in an intrahepatic model.

1 reference

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Pivotal role of mTOR signaling in hepatocellular carcinoma

1 reference

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

1 reference

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

1 reference

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

1 reference

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Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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Hepatocellular carcinoma: current management and future trends.

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

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The TOR pathway: a target for cancer therapy

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Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

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Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis

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Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival

1 reference

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Gene expression patterns in human liver cancers

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma.

1 reference

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1 reference

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12 December 2020

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP21260

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

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