(Q36583648)

English

Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells

scientific article published on 16 February 2016

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells (English)

1 reference

Europe PubMed Central

15 August 2017

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inferred from title

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based on heuristic

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Anna Klimaszewska-Wisniewska

1

1 reference

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13 June 2020

4

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13 June 2020

6

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Alina Grzanka

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13 June 2020

Dariusz Grzanka

5

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Dariusz Grzanka

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13 June 2020

author name string

Marta Halas-Wisniewska

2

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13 June 2020

Tadeusz Tadrowski

3

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13 June 2020

publication date

16 February 2016

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15 August 2017

Cancer Cell International

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13 June 2020

16

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13 June 2020

10

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13 June 2020

https://scigraph.springernature.com/pub.10.1186/s12935-016-0288-3

0 references

A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089.

1 reference

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9 September 2017

An autophagic switch in the response of tumor cells to radiation and chemotherapy

1 reference

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9 September 2017

Cancer statistics, 2014

1 reference

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9 September 2017

Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells

1 reference

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9 September 2017

Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapies

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9 September 2017

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

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9 September 2017

Peneciraistin C induces caspase-independent autophagic cell death through mitochondrial-derived reactive oxygen species production in lung cancer cells

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9 September 2017

Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

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9 September 2017

Assessing the effectiveness and safety of liposomal paclitaxel in combination with cisplatin as first-line chemotherapy for patients with advanced NSCLC with regional lymph-node metastasis: study protocol for a randomized controlled trial (PLC-GC tr

1 reference

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9 September 2017

Chemotherapy and dietary phytochemical agents

1 reference

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9 September 2017

Efficient selection of genetically modified human T cells using methotrexate-resistant human dihydrofolate reductase.

1 reference

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9 September 2017

Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin

1 reference

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9 September 2017

Autophagy: for better or for worse

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9 September 2017

A switch between cytoprotective and cytotoxic autophagy in the radiosensitization of breast tumor cells by chloroquine and vitamin D.

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9 September 2017

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

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Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy

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9 September 2017

Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin

1 reference

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9 September 2017

The dual role of autophagy in cancer

1 reference

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9 September 2017

Autophagic cell death: Loch Ness monster or endangered species?

1 reference

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9 September 2017

Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice

1 reference

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9 September 2017

A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering

1 reference

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9 September 2017

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754822

9 September 2017

Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent

1 reference

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9 September 2017

Autophagy: assays and artifacts

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9 September 2017

Mechanisms of drug-induced mitotic catastrophe in cancer cells

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9 September 2017

Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells

1 reference

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9 September 2017

A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells

1 reference

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9 September 2017

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754822

9 September 2017

Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization.

1 reference

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9 September 2017

Preclinical versus clinical drug combination studies

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9 September 2017

Death through a tragedy: mitotic catastrophe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754822

9 September 2017

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754822

9 September 2017

Self-eating and self-killing: crosstalk between autophagy and apoptosis

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9 September 2017

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

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9 September 2017

Role for Rab7 in maturation of late autophagic vacuoles

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9 September 2017

Autophagy as a cell death and tumor suppressor mechanism

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9 September 2017

Cell death by mitotic catastrophe: a molecular definition

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9 September 2017

Microtubules as a target for anticancer drugs

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9 September 2017

Cancer chemoprevention with dietary phytochemicals

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9 September 2017

Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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9 September 2017

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

1 reference

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A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles

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9 September 2017

Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells'

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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

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9 September 2017

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9 September 2017

Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy

1 reference

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30 September 2017

Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells

1 reference

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30 September 2017

Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors.

1 reference

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30 September 2017

Involvement of the ERK signaling pathway in fisetin reduces invasion and migration in the human lung cancer cell line A549.

1 reference

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30 September 2017

Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo

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30 September 2017

Differential activity of caspase-3 regulates susceptibility of lung and breast tumor cell lines to Paclitaxel

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30 September 2017

Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

1 reference

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30 September 2017

Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo.

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30 September 2017

Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells

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30 September 2017

Centrosome impairments and consequent cytokinesis defects are possible mechanisms of taxane drugs.

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30 September 2017

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30 September 2017

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30 September 2017

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

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30 September 2017

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30 September 2017

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

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28 June 2018

A proposal regarding reporting of in vitro testing results

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28 June 2018

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28 June 2018

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28 June 2018

Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells

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20 September 2018

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20 September 2018

Novel antiproliferative flavonoids induce cell cycle arrest in human prostate cancer cell lines

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20 September 2018

Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy

1 reference

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20 September 2018

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20 September 2018

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20 September 2018

Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance.

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20 September 2018

A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines

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20 September 2018

Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-agent paclitaxel in the treatment of advanced non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26884726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalph

1 reference

https://pubmed.ncbi.nlm.nih.gov/26884726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26884726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12935-016-0288-3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26884726%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26884726%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26884726%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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