(Q36583985)

15 August 2017

1 reference

28 May 2020

CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential (English)

1 reference

non-small-cell lung carcinoma

15 August 2017

1 reference

28 May 2020

1 reference

28 May 2020

C-X-C motif chemokine ligand 12

1 reference

C-X-C motif chemokine receptor 4

20 November 2019

1 reference

15 December 2019

Ori Wald

1

1 reference

15 August 2017

Oz M Shapira

series ordinal

2

1 reference

15 August 2017

Uzi Izhar

series ordinal

3

1 reference

15 August 2017

language of work or name

1 reference

13 January 2013

7 references

15 August 2017

3 April 2019

31 July 2019

3 August 2019

20 November 2019

15 December 2019

28 May 2020

6 references

15 August 2017

31 July 2019

3 August 2019

20 November 2019

15 December 2019

28 May 2020

3

1 reference

15 August 2017

1

1 reference

15 August 2017

26-33

1 reference

Creative Commons Attribution-NonCommercial-NoDerivatives

15 August 2017

6 references

3 April 2019

31 July 2019

3 August 2019

20 November 2019

15 December 2019

28 May 2020

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Differential estrogen-regulation of CXCL12 chemokine receptors, CXCR4 and CXCR7, contributes to the growth effect of estrogens in breast cancer cells

9 September 2017

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PET imaging of CXCR4 using copper-64 labeled peptide antagonist

9 September 2017

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Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells

9 September 2017

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Concise review: Emerging concepts in clinical targeting of cancer stem cells

9 September 2017

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Potential of CXCR4 antagonists for the treatment of metastatic lung cancer

9 September 2017

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New driver mutations in non-small-cell lung cancer

9 September 2017

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9 September 2017

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Lung cancer stem cell: new insights on experimental models and preclinical data.

9 September 2017

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PET of tumor CXCR4 expression with 4-18F-T140.

9 September 2017

1 reference

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Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC.

9 September 2017

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Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer

9 September 2017

1 reference

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9 September 2017

Cancer statistics, 2010

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Cell of origin of lung cancer.

9 September 2017

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Lung cancer stem cells as a target for therapy

9 September 2017

1 reference

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Management of patients with advanced non-small cell lung cancer: current and emerging options

9 September 2017

1 reference

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Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop

9 September 2017

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Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

9 September 2017

1 reference

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The new lung cancer staging system

9 September 2017

1 reference

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The AMD3100 story: the path to the discovery of a stem cell mobilizer (Mozobil).

9 September 2017

1 reference

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The CXCR4/SDF-1 chemokine receptor axis: a new target therapeutic for non-small cell lung cancer

9 September 2017

1 reference

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CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

9 September 2017

1 reference

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Chemokines and chemokine receptors in stem cell circulation

9 September 2017

1 reference

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Control of chemokine-guided cell migration by ligand sequestration

9 September 2017

1 reference

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Identification and expansion of the tumorigenic lung cancer stem cell population

9 September 2017

1 reference

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Epidemiology of Lung Cancer

9 September 2017

1 reference

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Role of chemokines in tumor growth

9 September 2017

1 reference

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9 September 2017

Cancer statistics, 2007

1 reference

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A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

9 September 2017

1 reference

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

One hundred years of lung cancer

9 September 2017

1 reference

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How do stem cells find their way home?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The therapeutic potential of CXCR4 antagonists in the treatment of HIV.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Involvement of chemokine receptors in breast cancer metastasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Chemokines: a new classification system and their role in immunity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non-small cell lung cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Interaction between neoplastic cells and cancer-associated fibroblasts through the CXCL12/CXCR4 axis: role in non-small cell lung cancer tumor proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Regulation of the chemokine receptor CXCR4 and metastasis by hypoxia-inducible factor in non small cell lung cancer cell lines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Human melanoma metastases express functional CXCR4.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Stromal-derived factor-1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Chipping away at the lung cancer genome.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Five-year survival does not equal cure in non-small cell lung cancer: a Surveillance, Epidemiology, and End Results-based analysis of variables affecting 10- to 18-year survival

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

CXCL12-binding receptors expression in non-small cell lung cancer relates to tumoral microvascular density and CXCR4 positive circulating tumoral cells in lung draining venous blood

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

CXCR4 overexpression is associated with poor outcome in females diagnosed with stage IV non-small cell lung cancer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Association of genetic polymorphisms of CXCL12/SDF1 gene and its receptor, CXCR4, to the susceptibility and prognosis of non-small cell lung cancer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Evaluation of the new TNM staging system proposed by the International Association for the Study of Lung Cancer at a single institution

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Contribution of genetic polymorphisms of stromal cell-derived factor-1 and its receptor, CXCR4, to the susceptibility and clinicopathologic development of oral cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

CXCL12 and CXCR4 in adenocarcinoma of the lung: association with metastasis and survival.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563078

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

4 December 2018

1 reference

12 December 2020

1 reference

12 December 2020

Winning the Battle, Losing the War: The Noncurative “Curative” Resection for Stage I Adenocarcinoma of the Lung

1 reference

12 December 2020

High-level CXCR4 expression correlates with brain-specific metastasis of non-small cell lung cancer

1 reference

12 December 2020

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

1 reference

12 December 2020

Identifiers

DOI

10.7150/THNO.4922

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23382783

1 reference