(Q36585134)

15 August 2017

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title

Molecular regulation of osteoclast activity (English)

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15 August 2017

1

Angela Bruzzaniti

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15 August 2017

Roland Baron

2

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15 August 2017

1 June 2006

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Reviews in Endocrine and Metabolic Disorders

15 August 2017

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15 August 2017

7

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15 August 2017

1-2

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15 August 2017

123-139

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https://scigraph.springernature.com/pub.10.1007/s11154-006-9009-x

15 August 2017

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cites work

The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Differential Control of CD28-Regulated In Vivo Immunity by the E3 Ligase Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Molecular cloning and expression of a unique rabbit osteoclastic phosphotyrosyl phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Regulatory mechanisms of dynamin-dependent endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Differential distribution of dynamin isoforms in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Rac-GTPase, osteoclast cytoskeleton and bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-006-9009-X

Colony-stimulating factor-1 stimulates the formation of multimeric cytosolic complexes of signaling proteins and cytoskeletal components in macrophages

21 January 2018

1 reference

12 December 2020

Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures

1 reference

12 December 2020

Signaling through focal adhesion kinase

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12 December 2020

Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones

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12 December 2020

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein

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12 December 2020

Tyrosine phosphorylation of beta3 integrin provides a binding site for Pyk2.

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12 December 2020

Negative receptor signalling

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12 December 2020

Protein kinase C antagonizes pertussis-toxin-sensitive coupling of the calcitonin receptor to adenylyl cyclase

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12 December 2020

Integrin-mediated signaling in the regulation of osteoclast adhesion and activation.

1 reference

12 December 2020

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

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12 December 2020

Osteoclasts express high levels of pp60c-src in association with intracellular membranes

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12 December 2020

Association of Cbl with Fms and p85 in response to macrophage colony-stimulating factor.

1 reference

12 December 2020

Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor

1 reference

12 December 2020

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

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12 December 2020

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

1 reference

12 December 2020

Endophilin-1: a multifunctional protein

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12 December 2020

Integrin-mediated signals regulated by members of the rho family of GTPases

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12 December 2020

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells

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12 December 2020

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

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12 December 2020

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

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12 December 2020

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12 December 2020

Structure and regulation of Src family kinases

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12 December 2020

Tumor Necrosis Factor α Regulatesαvβ5Integrin Expression by Osteoclast Precursorsin Vitro and in Vivo1

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12 December 2020

Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

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12 December 2020

Rho GTPases in cell biology

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12 December 2020

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

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12 December 2020

Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone.

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12 December 2020

Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2.

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12 December 2020

Inhibition of osteoclastic bone resorption in vivo by echistatin, an "arginyl-glycyl-aspartyl" (RGD)-containing protein

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12 December 2020

ArgGlyAsp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts*1

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12 December 2020

A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo

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12 December 2020

Tyrosine phosphorylation of p130Cas is involved in actin organization in osteoclasts.

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12 December 2020

Activation of Pyk2/RAFTK induces tyrosine phosphorylation of alpha-synuclein via Src-family kinases

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12 December 2020

The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain

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12 December 2020

Activation of the integrin alpha v beta 3 involves a discrete cation-binding site that regulates conformation

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12 December 2020

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

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12 December 2020

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

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12 December 2020

Distribution of integrin subunits on rat metaphyseal osteoclasts and osteoblasts

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12 December 2020

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

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12 December 2020

Calcitonin down-regulates immediate cell signals induced in human osteoclast-like cells by the bone sialoprotein-IIA fragment through a postintegrin receptor mechanism

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12 December 2020

Osteoblasts release osteoclasts from calcitonin-induced quiescence

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12 December 2020

Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions

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12 December 2020

Signal transduction pathways regulating osteoclast differentiation and function

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12 December 2020

Regulatory mechanisms operative in osteoclasts

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12 December 2020

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

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12 December 2020

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

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12 December 2020

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

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12 December 2020

Histomorphometric evidence for echistatin inhibition of bone resorption in mice with secondary hyperparathyroidism

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12 December 2020

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

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12 December 2020

A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function

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12 December 2020

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

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12 December 2020

A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts

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12 December 2020

Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

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12 December 2020

Spatial organization of microfilaments and vitronectin receptor, alpha v beta 3, in osteoclasts. A study using confocal laser scanning microscopy

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12 December 2020

Dynamin: characteristics, mechanism of action and function.

1 reference

12 December 2020

Regulating actin dynamics at membranes: a focus on dynamin

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12 December 2020

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

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12 December 2020

Osteoclast integrin alphaVbeta3 is present in the clear zone and contributes to cellular polarization

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12 December 2020

Deconstructing gelsolin: identifying sites that mimic or alter binding to actin and phosphoinositides

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12 December 2020

A cloned porcine renal calcitonin receptor couples to adenylyl cyclase and phospholipase C

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12 December 2020

Echistatin is a potent inhibitor of bone resorption in culture

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12 December 2020

Podosomes in osteoclast-like cells: structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin alphaVbeta3.

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12 December 2020

Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin

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12 December 2020

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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12 December 2020

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12 December 2020

The cell biology of osteoclast function.

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12 December 2020

Removal of osteoclast bone resorption products by transcytosis

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12 December 2020

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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12 December 2020

Focal adhesions, contractility, and signaling

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12 December 2020

A tyrosine-based sorting signal in the beta2 integrin cytoplasmic domain mediates its recycling to the plasma membrane and is required for ligand-supported migration

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12 December 2020

Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.

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12 December 2020

Rho-A is critical for osteoclast podosome organization, motility, and bone resorption

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12 December 2020

Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts

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12 December 2020

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

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12 December 2020

Molecular links between endocytosis and the actin cytoskeleton.

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12 December 2020

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation

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12 December 2020

Cytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinase

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12 December 2020

Beta 3 subunit of vitronectin receptor is present in osteoclast adhesion structures and not in other monocyte-macrophage derived cells

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12 December 2020

Vinculin, talin, and integrins are localized at specific adhesion sites of malignant B lymphocytes

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12 December 2020

Organization of functional domains in the docking protein p130Cas

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12 December 2020

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

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12 December 2020

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

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12 December 2020

A Glanzmann's mutation in beta 3 integrin specifically impairs osteoclast function

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12 December 2020

Role of c-Src in cellular events associated with colony-stimulating factor-1-induced spreading in osteoclasts

1 reference

12 December 2020

The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C

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12 December 2020

Antibody to beta3 integrin inhibits osteoclast-mediated bone resorption in the thyroparathyroidectomized rat

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12 December 2020

Integrin engagement, the actin cytoskeleton, and c-Src are required for the calcitonin-induced tyrosine phosphorylation of paxillin and HEF1, but not for calcitonin-induced Erk1/2 phosphorylation

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12 December 2020

Cellular functions regulated by Src family kinases

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12 December 2020

Phosphatidylinositol 3-kinase association with the osteoclast cytoskeleton, and its involvement in osteoclast attachment and spreading

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12 December 2020

The integrin ligand echistatin prevents bone loss in ovariectomized mice and rats

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12 December 2020

p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration

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12 December 2020

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

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12 December 2020

Optimal bone resorption by isolated rat osteoclasts requires chloride/bicarbonate exchange

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12 December 2020

The molecular dynamics of osteoclast adhesions

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12 December 2020

Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells

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12 December 2020

Evidence that the action of calcitonin on rat osteoclasts is mediated by two G proteins acting via separate post-receptor pathways

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12 December 2020

The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutants

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12 December 2020

Osteopontin--a possible anchor of osteoclasts to bone

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12 December 2020

Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification

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12 December 2020

Rho and Rac exert antagonistic functions on spreading of macrophage-derived multinucleated cells and are not required for actin fiber formation.

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12 December 2020

Accessory factors in clathrin-dependent synaptic vesicle endocytosis

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12 December 2020

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.

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12 December 2020

Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity

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12 December 2020

Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts

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12 December 2020

Abnormal localisation and hyperclustering of (alpha)(V)(beta)(3) integrins and associated proteins in Src-deficient or tyrphostin A9-treated osteoclasts

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12 December 2020

Immunofluorescent evidence for the abundance of focal adhesion kinase in the human and avian osteoclasts and its down regulation by calcitonin

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12 December 2020

Effects of kistrin on bone resorption in vitro and serum calcium in vivo

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12 December 2020

Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia

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12 December 2020

Trafficking of Matrix Collagens Through Bone-Resorbing Osteoclasts

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12 December 2020

Effect of parathyroid hormone and calcitonin on the cytoplasmic spreading of isolated osteoclasts

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12 December 2020

Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone

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12 December 2020

The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction

1 reference

12 December 2020

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

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12 December 2020

Localization and possible role of two different alpha v beta 3 integrin conformations in resting and resorbing osteoclasts.

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12 December 2020

Ultrastructural effects of calcitonin on osteoclasts in tissue culture

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12 December 2020

Vitronectin receptor has a role in bone resorption but does not mediate tight sealing zone attachment of osteoclasts to the bone surface

1 reference

12 December 2020

Rho GTPases and their effector proteins

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12 December 2020

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1 reference

12 December 2020

Modulation of osteoclast differentiation

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12 December 2020

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

1 reference

12 December 2020

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

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12 December 2020

Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

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12 December 2020

Rho family proteins and cell migration

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12 December 2020

Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts

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12 December 2020

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border

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12 December 2020

Antitumor vaccine effect of irradiated murine neuroblastoma cells producing interleukin-2 or granulocyte macrophage-colony stimulating factor.

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12 December 2020

Signaling and endocytosis: a team effort for cell migration

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12 December 2020

Src family kinases, key regulators of signal transduction

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12 December 2020

Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk

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12 December 2020

Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts

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12 December 2020

The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

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12 December 2020

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

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12 December 2020

PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption

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12 December 2020

A functional link between dynamin and the actin cytoskeleton at podosomes

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12 December 2020

Antisense oligodeoxynucleotide evidence that a unique osteoclastic protein-tyrosine phosphatase is essential for osteoclastic resorption.

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12 December 2020

Dynamin:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis

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12 December 2020

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12 December 2020

Podosomes: adhesion hot-spots of invasive cells

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12 December 2020

Src kinase activity is essential for osteoclast function

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12 December 2020

Tyrosine Phosphatase Epsilon Is a Positive Regulator of Osteoclast Function in Vitro and In Vivo

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12 December 2020

Mutations in the a3 subunit of the vacuolar H(+)-ATPase cause infantile malignant osteopetrosis

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12 December 2020

Osteoclasts, integrins, and osteoporosis.

1 reference

12 December 2020

Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis

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12 December 2020

FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation

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12 December 2020

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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12 December 2020

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

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12 December 2020

Soluble alpha v beta 3-integrin ligands raise [Ca2+]i in rat osteoclasts and mouse-derived osteoclast-like cells

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12 December 2020

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

1 reference

12 December 2020

Gelsolin-polyphosphoinositide interaction. Full expression of gelsolin-inhibiting function by polyphosphoinositides in vesicular form and inactivation by dilution, aggregation, or masking of the inositol head group

1 reference

12 December 2020

Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor.

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12 December 2020

Differentiation dependent expression of tensin and cortactin in chicken osteoclasts.

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12 December 2020

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization

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12 December 2020

Osteoclastic bone resorption by a polarized vacuolar proton pump

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12 December 2020

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

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12 December 2020

Vav3 regulates osteoclast function and bone mass

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12 December 2020

Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration.

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12 December 2020

Aggregation of mononucleated precursors triggers cell surface expression of alphavbeta3 integrin, essential to formation of osteoclast-like multinucleated cells.

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12 December 2020

Apatite-mediated actin dynamics in resorbing osteoclasts

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12 December 2020

Genetic regulation of osteoclast development and function

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12 December 2020

Deletion of the Src homology 3 domain and C-terminal proline-rich sequences in Bcr-Abl prevents Abl interactor 2 degradation and spontaneous cell migration and impairs leukemogenesis

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12 December 2020

c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation

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12 December 2020

The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily

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12 December 2020

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

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12 December 2020

SH3P2 in complex with Cbl and Src.

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12 December 2020

New roles for Src kinases in control of cell survival and angiogenesis

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12 December 2020

A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways

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12 December 2020

Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin

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12 December 2020

c-Cbl localizes to actin lamellae and regulates lamellipodia formation and cell morphology

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12 December 2020

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

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12 December 2020

WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption

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12 December 2020

PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

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12 December 2020

Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain

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12 December 2020

Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength

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12 December 2020

Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

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12 December 2020

Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway

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12 December 2020

The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

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12 December 2020

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

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12 December 2020

Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)

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12 December 2020

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

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12 December 2020

Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis

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12 December 2020

Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis

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12 December 2020

Rat osteoclast precursors in vivo express a vitronectin receptor and a chloride-bicarbonate exchanger.

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12 December 2020

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

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12 December 2020

The effects of parathyroid hormone, colchicine, and calcitonin on the ultrastructure and the activity of osteoclasts in organ culture

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12 December 2020

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice

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12 December 2020

The role of phosphoinositide 3-kinase in spreading osteoclasts induced by colony-stimulating factor-1.

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12 December 2020

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

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12 December 2020

Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones

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12 December 2020

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

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12 December 2020

Possible involvement of focal adhesion kinase, p125FAK, in osteoclastic bone resorption.

1 reference

12 December 2020

The calcitonin receptor stimulates Shc tyrosine phosphorylation and Erk1/2 activation. Involvement of Gi, protein kinase C, and calcium.

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12 December 2020

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

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12 December 2020

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

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12 December 2020

From signal to pseudopod. How cells control cytoplasmic actin assembly.

1 reference

12 December 2020

Negative regulation of myeloid cell proliferation and function by the SH2 domain-containing tyrosine phosphatase-1.

1 reference

12 December 2020

Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts

1 reference

12 December 2020

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

1 reference

12 December 2020

The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice

1 reference

12 December 2020

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

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12 December 2020

Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins

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12 December 2020

The effects of rhGM-CSF on macrophage function

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12 December 2020

Mechanisms of osteoclast dysfunction in human osteopetrosis: abnormal osteoclastogenesis and lack of osteoclast-specific adhesion structures.

1 reference

12 December 2020

10.1007/S11154-006-9009-X

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16951988