(Q36586957)

15 August 2017

1 reference

title

Guarding the immune system: suppression of autoimmunity by CD4+CD25+ immunoregulatory T cells (English)

1 reference

15 August 2017

Tricia D Zwar

1

1 reference

PubMed ID

16956386

15 August 2017

Ian R van Driel

series ordinal

2

1 reference

PubMed ID

16956386

15 August 2017

Paul A Gleeson

series ordinal

3

1 reference

15 August 2017

5 September 2006

1 reference

Immunology & Cell Biology

15 August 2017

1 reference

15 August 2017

84

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15 August 2017

487-501

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15 August 2017

6

1 reference

Do suppressor T cells exist?

15 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulating the immune response to transplants. a role for CD4+ regulatory cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulatory T cells in autoimmmunity*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Human CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Mechanisms of suppression by suppressor T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

A function for interleukin 2 in Foxp3-expressing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Costimulatory regulation of T cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CTLA-4 and T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Forkhead-box transcription factors and their role in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4+ CD25+ regulatory T cell repertoire formation in response to varying expression of a neo-self-antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Tolerance, not immunity, crucially depends on IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulation of mature T cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Dynamics of suppressor T cells: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

In vivo instruction of suppressor commitment in naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Regulation of immunity by self-reactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

How alpha beta T-cell receptors 'see' peptide/MHC complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

A role for TCR affinity in regulating naive T cell homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Natural regulatory T cells in infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Peripheral autoantigen induces regulatory T cells that prevent autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1711.2006.01471.X

10.1111/J.1440-1711.2006.01471.X

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16956386