(Q36587959)

English

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

scientific article published on 5 December 2012

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes (English)

1 reference

Europe PubMed Central

15 August 2017

endoplasmic reticulum

1 reference

based on heuristic

inferred from title

protein ubiquitination

1 reference

based on heuristic

inferred from title

author name string

Youngah Jo

1

1 reference

Europe PubMed Central

15 August 2017

Isamu Z Hartman

2

1 reference

Europe PubMed Central

15 August 2017

Russell A DeBose-Boyd

3

1 reference

Europe PubMed Central

15 August 2017

publication date

5 December 2012

1 reference

Europe PubMed Central

15 August 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

15 August 2017

24

1 reference

Europe PubMed Central

15 August 2017

3

1 reference

Europe PubMed Central

15 August 2017

169-183

1 reference

Europe PubMed Central

15 August 2017

Lipid droplets and cellular lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

BAT3 guides misfolded glycoproteins out of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Lipid droplet formation is dispensable for endoplasmic reticulum-associated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems

1 reference

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9 September 2017

Not just fat: the structure and function of the lipid droplet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Protein quality control as a strategy for cellular regulation: lessons from ubiquitin-mediated regulation of the sterol pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step

1 reference

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9 September 2017

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

1 reference

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UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

1 reference

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A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

1 reference

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Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic

1 reference

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Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies.

1 reference

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9 September 2017

Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Lipid droplets: a unified view of a dynamic organelle

1 reference

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9 September 2017

Protein sensors for membrane sterols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Membrane topology of human insig-1, a protein regulator of lipid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Mechanism of ubiquitin recognition by the CUE domain of Vps9p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564538

9 September 2017

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

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Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

1 reference

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

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9 September 2017

Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

1 reference

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Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction

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Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi

1 reference

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Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

1 reference

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Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

1 reference

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Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

1 reference

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Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein

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Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.

1 reference

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Lipid droplets finally get a little R-E-S-P-E-C-T.

1 reference

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Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

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Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe.

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Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

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Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

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19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

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12 December 2020

based on heuristic

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Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triacsins, new inhibitors of acyl-CoA synthetase produced by Streptomyces sp

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223569

12 December 2020

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Proteins under new management: lipid droplets deliver

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E12-07-0564

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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