(Q36590567)

15 August 2017

1 reference

title

Activation-induced cytidine deaminase: structure-function relationship as based on the study of mutants (English)

1 reference

15 August 2017

4

Alain Fischer

0 references

Sophie Peron

object named as

Sophie Peron

series ordinal

2

0 references

Anne Durandy

object named as

Anne Durandy

series ordinal

1

0 references

Nadine Taubenheim

series ordinal

3

object named as

Nadine Taubenheim

1 reference

15 August 2017

language of work or name

1 reference

1 December 2006

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15 August 2017

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15 August 2017

volume

27

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15 August 2017

issue

12

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15 August 2017

page(s)

1185-1191

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Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Increased transcription levels induce higher mutation rates in a hypermutating cell line

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Maturation of the immune response in germinal centers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Mismatch repair co-opted by hypermutation.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Roles for mismatch repair factors in regulating genetic recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Processing of switch transcripts is required for targeting of antibody class switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Indirect and direct evidence for DNA double-strand breaks in hypermutating immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The liaison of isotype class switch and mismatch repair: an illegitimate affair

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Unique and unprecedented recombination mechanisms in class switching

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Nibrin functions in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Delineation of the role of the Mre11 complex in class switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Mechanism of antigen-driven selection in germinal centres

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The AID enzyme induces class switch recombination in fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

ATM is required for efficient recombination between immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Progress in understanding the mechanism and consequences of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Follicular B helper T cells in antibody responses and autoimmunity.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The double-edged sword of activation-induced cytidine deaminase.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20414

7 January 2021

Identifiers

DOI

10.1002/HUMU.20414

1 reference

15 August 2017

1 reference