(Q36600251)

15 August 2017

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title

Telomerase-based immunotherapy of cancer (English)

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15 August 2017

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Erica L Carpenter

1

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15 August 2017

Robert H Vonderheide

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Expert Opinion on Biological Therapy

15 August 2017

published in

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15 August 2017

volume

6

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15 August 2017

issue

10

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15 August 2017

page(s)

1031-1039

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Telomerase as a universal tumor-associated antigen for cancer immunotherapy

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.10.1031

From cancer genomics to cancer immunotherapy: toward second-generation tumor antigens

21 January 2018

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Human telomerase and its regulation

21 January 2018

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Telomerase activation, cellular immortalization and cancer

21 January 2018

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Telomerase: a target for cancer therapeutics

21 January 2018

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Switching and signaling at the telomere

21 January 2018

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Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

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Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

21 January 2018

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Human telomerase contains evolutionarily conserved catalytic and structural subunits

21 January 2018

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Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

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Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

21 January 2018

1 reference

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The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes

21 January 2018

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Cytotoxic T cell immunity against telomerase reverse transcriptase in humans

21 January 2018

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Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes

21 January 2018

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HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy

21 January 2018

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Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells.

21 January 2018

1 reference

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Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

21 January 2018

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Immunogenic HLA-B*0702-restricted epitopes derived from human telomerase reverse transcriptase that elicit antitumor cytotoxic T-cell responses.

21 January 2018

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Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma

21 January 2018

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Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase

21 January 2018

1 reference

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Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.

21 January 2018

1 reference

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Artificial antigen-presenting cells transduced with telomerase efficiently expand epitope-specific, human leukocyte antigen-restricted cytotoxic T cells

21 January 2018

1 reference

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Frequency of telomerase-specific CD8+ T lymphocytes in patients with cancer.

21 January 2018

1 reference

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Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes.

21 January 2018

1 reference

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Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy

21 January 2018

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High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy.

21 January 2018

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

1 reference

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Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors

21 January 2018

1 reference

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Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

21 January 2018

1 reference

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Telomeres and telomerase in normal and malignant haematopoietic cells

21 January 2018

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Expression of TERT in early premalignant lesions and a subset of cells in normal tissues

21 January 2018

1 reference

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Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.10.1031

Telomerase vaccination has no detectable effect on SCID-repopulating and colony-forming activities in the bone marrow of cancer patients.

21 January 2018

1 reference

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A controlled trial of a human papillomavirus type 16 vaccine

21 January 2018

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Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.10.1031

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.10.1031

Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

21 January 2018

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Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.10.1031

10.1517/14712598.6.10.1031

21 January 2018

Identifiers

DOI

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15 August 2017

1 reference