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Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling
scientific article published on 18 January 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
title
Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
main subject
NF-κB
1 reference
based on heuristic
inferred from title
author
Shitao Li
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
author name string
Yuwei Di
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Lingyan Wang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Ye Zhang
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Martin E Dorf
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
publication date
18 January 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
number of pages
9
1 reference
based on heuristic
inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
volume
20
1 reference
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Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
page(s)
705-713
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
cites work
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
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PubMed Central
reference URL
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MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages
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NF-kappaB and the immune response
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PubMed Central
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MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells
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30 September 2017
Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation
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PubMed Central
reference URL
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Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways
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TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation
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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
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Dimerization through the catalytic domain is essential for MEKK2 activation.
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Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells
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30 September 2017
NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling
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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway
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Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
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Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
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The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase
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30 September 2017
TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway
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30 September 2017
TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1
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Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166
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30 September 2017
The essential role of MEKK3 in TNF-induced NF-kappaB activation
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30 September 2017
Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1
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PubMed Central
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30 September 2017
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop
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PubMed Central
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30 September 2017
Mekk3 is essential for early embryonic cardiovascular development
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MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway
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Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative
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20 September 2018
The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation
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20 September 2018
TLR8-mediated NF-κB and JNK Activation Are TAK1-independent and MEKK3-dependent
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Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification
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Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation
1 reference
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PubMed
reference URL
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELLSIG.2007.12.007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PMC publication ID
2362106
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed publication ID
18206350
1 reference
stated in
Europe PubMed Central
PMC publication ID
2362106
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
ResearchGate publication ID
5645977
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