(Q36619427)

English

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.

scientific article published on February 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

14

object named as

Pierre Chambon

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Gabriel L Galea

object named as

Gabriel L Galea

8

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Cecilia Engdahl

object named as

Cecilia Engdahl

10

0 references

Marie K Lagerquist

object named as

Marie K Lagerquist

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object named as

Klara Sjögren

11

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object named as

Sara H Windahl

1

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object named as

Lee B Meakin

9

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object named as

Claes Ohlsson

17

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Anna E Börjesson

object named as

Anna E Börjesson

3

0 references

object named as

Ulf H Lerner

7

0 references

2

object named as

Leanne Saxon

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

13

object named as

Andrée Krust

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Baruch Frenkel

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Petra Henning

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Maria C Antal

12

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Lance E Lanyon

15

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Joanna S Price

16

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

1 February 2013

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Bone and Mineral Research

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

28

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

291-301

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Regulation of osteoblast differentiation by interleukin-11 via AP-1 and Smad signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Phosphorylation of Estrogen Receptor α at serine 118 directs recruitment of promoter complexes and gene-specific transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Using digital image correlation to determine bone surface strains during loading and after adaptation of the mouse tibia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Is estrogen receptor alpha key to controlling bones' resistance to fracture?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Estrogen deposits extra mineral into bones of female rats in puberty, but simultaneously seems to suppress the responsiveness of female skeleton to mechanical loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Identification of estrogen-regulated genes of potential importance for the regulation of trabecular bone mineral density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Sex steroids and the construction and conservation of the adult skeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Mechanical strain and estrogen activate estrogen receptor alpha in bone cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Deterring bone loss by exercise intervention in premenopausal and postmenopausal women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

30 September 2017

Estrogen receptors α and β have different gender-dependent effects on the adaptive responses to load bearing in cancellous and cortical bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Mechanical strain activates estrogen response elements in bone cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Bone "mass" and the "mechanostat": a proposal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Effect of long-distance running on bone mass in women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

28 June 2018

Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Skeletal effects of estrogen and mechanical loading are structurally distinct.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Identification of target cells for the genomic effects of estrogens in bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor-beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Low-dose estrogen treatment suppresses periosteal bone formation in response to mechanical loading.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Tissue- and time-dependent estrogen receptor activation in estrogen reporter mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

High-impact exercise strengthens bone in osteopenic ovariectomized rats with the same outcome as Sham rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Fluid shear stress increases interleukin-11 expression in human osteoblast-like cells: its role in osteoclast induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Two separate mechanisms for ligand-independent activation of the estrogen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575695

20 September 2018

Bone adaptation requires oestrogen receptor-α

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1754

21 January 2018

The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

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An improved segmentation method for in vivo microCT imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between exercise and pubertal BMD is modulated by estrogen receptor alpha genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ovariectomy on bone response to in vivo external loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor specificity for the effects of estrogen in ovariectomized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22972752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JBMR.1754

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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