(Q36621175)

PubMed publication ID

15 August 2017

1 reference

title

Disease-modifying pathways in neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

author name string

Steven Finkbeiner

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

Richard I Morimoto

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

Paul J Muchowski

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 October 2006

1 reference

PubMed publication ID

17035516

15 August 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

page(s)

10349-10357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

Kynurenine pathway metabolism in human astrocytes

11 May 2020

cites work

1 reference

12 December 2020

A one-hit model of cell death in inherited neuronal degenerations

1 reference

12 December 2020

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

1 reference

12 December 2020

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

1 reference

12 December 2020

Inflammation in neurodegenerative disease--a double-edged sword

1 reference

12 December 2020

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

1 reference

12 December 2020

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

1 reference

12 December 2020

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

1 reference

12 December 2020

Modifier genes and protective alleles in humans and mice

1 reference

12 December 2020

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

1 reference

12 December 2020

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

1 reference

12 December 2020

Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

1 reference

12 December 2020

Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting?

1 reference

12 December 2020

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

1 reference

12 December 2020

Inhibition of polyglutamine aggregate cytotoxicity by a structure-based elongation inhibitor

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12 December 2020

Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16.

1 reference

12 December 2020

Experimental therapeutics in transgenic mouse models of Huntington's disease

1 reference

12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

1 reference

12 December 2020

Neurodegenerative disease: neuron protection agency

1 reference

12 December 2020

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

12 December 2020

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

1 reference

12 December 2020

Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease

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12 December 2020

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

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12 December 2020

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

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12 December 2020

Automated microscope system for determining factors that predict neuronal fate.

1 reference

12 December 2020

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

1 reference

12 December 2020

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

12 December 2020

Autophagy: molecular machinery for self-eating

1 reference

12 December 2020

Progressive disruption of cellular protein folding in models of polyglutamine diseases.

1 reference

12 December 2020

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

1 reference

12 December 2020

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases

1 reference

12 December 2020

Consequences of the selective blockage of chaperone-mediated autophagy

1 reference

12 December 2020

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

12 December 2020

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

12 December 2020

Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice

1 reference

12 December 2020

Onset and progression in inherited ALS determined by motor neurons and microglia

1 reference

12 December 2020

Chaperone-mediated autophagy in aging and disease

1 reference

12 December 2020

Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model

1 reference

12 December 2020

Autophagy and aging: the importance of maintaining "clean" cells

1 reference

12 December 2020

Autophagy and its possible roles in nervous system diseases, damage and repair

1 reference

12 December 2020

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

12 December 2020

Model of Huntington's disease

1 reference

12 December 2020

Differential vulnerability of central neurons of the rat to quinolinic acid

1 reference

12 December 2020

Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

1 reference

12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

12 December 2020

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase

1 reference

12 December 2020

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?

1 reference

12 December 2020

10.1523/JNEUROSCI.3829-06.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674695&resulttype=core&format=json

11 May 2020

PubMed publication ID

17035516

1 reference