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Alsin and the molecular pathways of amyotrophic lateral sclerosis
scientific article published on 10 July 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
review article
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Europe PubMed Central
title
Alsin and the molecular pathways of amyotrophic lateral sclerosis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
main subject
amyotrophic lateral sclerosis
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author
Huaibin Cai
series ordinal
3
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stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author name string
Jayanth Chandran
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Jinhui Ding
series ordinal
2
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stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
publication date
10 July 2007
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Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
published in
Molecular Neurobiology
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
volume
36
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
page(s)
224-231
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s12035-007-0034-x
0 references
cites work
Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.
1 reference
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PubMed Central
reference URL
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retrieved
30 September 2017
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking
1 reference
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PubMed Central
reference URL
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30 September 2017
Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1(G93A) transgenic mice
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PubMed Central
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30 September 2017
Alsin/Rac1 signaling controls survival and growth of spinal motoneurons
1 reference
stated in
PubMed Central
reference URL
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30 September 2017
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities
1 reference
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PubMed Central
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30 September 2017
Calcium-permeable AMPA channels in neurodegenerative disease and ischemia
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30 September 2017
The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function
1 reference
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PubMed Central
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30 September 2017
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
1 reference
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PubMed Central
reference URL
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Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse
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ALS syndrome in patients with HIV-1 infection
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30 September 2017
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
1 reference
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PubMed Central
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30 September 2017
Alsin is partially associated with centrosome in human cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364715
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30 September 2017
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364715
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30 September 2017
A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice
1 reference
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Distal spinal and bulbar muscular atrophy caused by dynactin mutation.
1 reference
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30 September 2017
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
1 reference
stated in
PubMed Central
reference URL
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ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics
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PubMed Central
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A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
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PubMed Central
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Lessons from models of SOD1-linked familial ALS.
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PubMed Central
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Unraveling the mechanisms involved in motor neuron degeneration in ALS
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PubMed Central
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Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor
1 reference
stated in
PubMed Central
reference URL
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Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants
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Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease
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The first nonsense mutation in alsin results in a homogeneous phenotype of infantile-onset ascending spastic paralysis with bulbar involvement in two siblings
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Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene
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The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
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1 reference
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reference URL
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Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17955197
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17955197
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel mutation in the ALS2 gene in juvenile amyotrophic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17955197
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lymphopenia and spontaneous autorosette formation in SOD1 mouse model of ALS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17955197
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S12035-007-0034-X
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PMC publication ID
2364715
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PubMed publication ID
17955197
1 reference
stated in
Europe PubMed Central
PMC publication ID
2364715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17955197%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
ResearchGate publication ID
5890971
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