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The insulin receptor: both a prototypical and atypical receptor tyrosine kinase.
scientific article published on March 2013
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Europe PubMed Central
PMC publication ID
3578362
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
title
The insulin receptor: both a prototypical and atypical receptor tyrosine kinase
(English)
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stated in
Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
author
Stevan R Hubbard
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
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24 February 2020
author name string
Stevan R Hubbard
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1
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Europe PubMed Central
PMC publication ID
3578362
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15 August 2017
language of work or name
English
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publication date
1 March 2013
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Europe PubMed Central
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3578362
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retrieved
24 February 2020
published in
Cold Spring Harbor Perspectives in Biology
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stated in
Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
volume
5
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Europe PubMed Central
PMC publication ID
3578362
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
issue
3
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Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
page(s)
a008946
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Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
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Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B
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30 September 2017
Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism
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30 September 2017
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
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30 September 2017
Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1
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30 September 2017
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene
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30 September 2017
Identification and characterization of novel substrates of Trk receptors in developing neurons
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30 September 2017
Identification of the rat adapter Grb14 as an inhibitor of insulin actions
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30 September 2017
Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]
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30 September 2017
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog
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30 September 2017
Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor
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30 September 2017
Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin
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30 September 2017
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30 September 2017
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30 September 2017
Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2
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30 September 2017
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
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30 September 2017
Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786
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30 September 2017
Crystal structure of the tyrosine kinase domain of the human insulin receptor
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30 September 2017
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
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30 September 2017
The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
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30 September 2017
The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals
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30 September 2017
IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85
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30 September 2017
YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase
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30 September 2017
Expression, characterization, and crystallization of the catalytic core of the human insulin receptor protein-tyrosine kinase domain
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30 September 2017
Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites
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28 June 2018
Mutation in a conserved motif next to the insulin receptor key autophosphorylation sites de-regulates kinase activity and impairs insulin action
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28 June 2018
Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation
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28 June 2018
The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors
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20 September 2018
A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.
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20 September 2018
Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region
1 reference
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4 December 2018
The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomain
1 reference
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reference URL
https://pubmed.ncbi.nlm.nih.gov/23457259
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphotyrosine binding domains of Shc and insulin receptor substrate 1 recognize the NPXpY motif in a thermodynamically distinct manner
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23457259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/CSHPERSPECT.A008946
1 reference
stated in
Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
PMC publication ID
3578362
1 reference
stated in
Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
PubMed publication ID
23457259
1 reference
stated in
Europe PubMed Central
PMC publication ID
3578362
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23457259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
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