(Q36629427)

English

Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial

scientific article published on 5 September 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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medulloblastoma

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Dominique Figarella-Branger

9

object named as

Dominique Figarella-Branger

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object named as

François Doz

10

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Birgitta Lannering

2

object named as

Birgitta Lannering

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Stefan Rutkowski

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object named as

Stefan Rutkowski

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Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Steven C Clifford

1

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Europe PubMed Central

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15 August 2017

Ed C Schwalbe

3

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Europe PubMed Central

PMC publication ID

15 August 2017

Debbie Hicks

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Kieran O'Toole

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Sarah Leigh Nicholson

6

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Europe PubMed Central

PMC publication ID

15 August 2017

Tobias Goschzik

7

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Europe PubMed Central

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15 August 2017

Anja Zur Mühlen

8

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Europe PubMed Central

PMC publication ID

15 August 2017

Göran Gustafsson

12

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Europe PubMed Central

PMC publication ID

15 August 2017

Torsten Pietsch

13

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Europe PubMed Central

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15 August 2017

SIOP-Europe PNET Group

14

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Europe PubMed Central

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15 August 2017

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publication date

5 September 2015

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Europe PubMed Central

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15 August 2017

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Europe PubMed Central

PMC publication ID

15 August 2017

6

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Europe PubMed Central

PMC publication ID

15 August 2017

36

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Europe PubMed Central

PMC publication ID

15 August 2017

38827-38839

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Cytogenetic prognostication within medulloblastoma subgroups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Medulloblastomics: the end of the beginning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Molecular subgroups of medulloblastoma: the current consensus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Medulloblastoma comprises four distinct molecular variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

The 2007 WHO classification of tumours of the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

The WHO classification of tumors of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

30 September 2017

An operative staging system and a megavoltage radiotherapeutic technic for cerebellar medulloblastomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

28 June 2018

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: results from the randomized multicenter HIT-SIOP PNET 4 trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Adult medulloblastoma comprises three major molecular variants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

"Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

A rapid and sensitive protocol for competitive reverse transcriptase (cRT) PCR analysis of cellular genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770740

20 September 2018

Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26420814

12 December 2020

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10.18632/ONCOTARGET.5149

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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