(Q36672143)

15 August 2017

Structure-activity relationship study of vitamin k derivatives yields highly potent neuroprotective agents (English)

1 reference

15 August 2017

0 references

1 reference

Benjamin J Josey

1

1 reference

15 August 2017

Elizabeth S Inks

series ordinal

2

1 reference

15 August 2017

Xuejun Wen

series ordinal

3

1 reference

15 August 2017

C James Chou

series ordinal

4

1 reference

15 August 2017

language of work or name

English

0 references

publication date

30 January 2013

1 reference

Journal of Medicinal Chemistry

15 August 2017

1 reference

15 August 2017

56

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15 August 2017

3

1 reference

15 August 2017

1007-1022

1 reference

describes a project that uses

15 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3593605/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3593605/fullTextXML

inferred from PubMed Central ID database lookup

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

30 September 2017

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Structure-activity relationship of novel menaquinone-4 analogues: modification of the side chain affects their biological activities.

30 September 2017

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A novel class of small molecule inhibitors of HDAC6.

30 September 2017

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Vitamin K has the potential to protect neurons from methylmercury-induced cell death in vitro

30 September 2017

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Injectable Lipid Emulsions—Advancements, Opportunities and Challenges

30 September 2017

1 reference

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Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

30 September 2017

1 reference

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Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

30 September 2017

1 reference

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UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy

30 September 2017

1 reference

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Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target

30 September 2017

1 reference

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Mitochondria, oxidative metabolism and cell death in stroke

30 September 2017

1 reference

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Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells

30 September 2017

1 reference

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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

30 September 2017

1 reference

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Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1.

30 September 2017

1 reference

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

30 September 2017

1 reference

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Medicinal chemical properties of successful central nervous system drugs

30 September 2017

1 reference

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

30 September 2017

1 reference

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Glutamate-induced oxidative stress, but not cell death, is largely dependent upon extracellular calcium in mouse neuronal HT22 cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity.

30 September 2017

1 reference

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Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

30 September 2017

1 reference

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Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents

30 September 2017

1 reference

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Mitochondrial fission in apoptosis, neurodegeneration and aging

30 September 2017

1 reference

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Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Oxytosis: A novel form of programmed cell death

30 September 2017

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

30 September 2017

1 reference

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

30 September 2017

1 reference

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30 September 2017

1 reference

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Mitochondrial control of cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Vitamin K-dependent proteins in the developing and aging nervous system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

The free radical theory of aging matures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

The role of monoamine metabolism in oxidative glutamate toxicity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Chemistry, nutritional sources, tissue distribution and metabolism of vitamin K with special reference to bone health

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Role of vitamin-K-dependent proteins in bone metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Regulation of sulfotransferase activity by vitamin K in mouse brain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Vitamin K status in human tissues: tissue-specific accumulation of phylloquinone and menaquinone-4.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Conversion of phylloquinone (Vitamin K1) into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

The activation of metabotropic glutamate receptors protects nerve cells from oxidative stress.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Utilization of operational schemes for analog synthesis in drug design

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593605

Oxidative stress in neurodegenerative diseases

20 September 2018

1 reference

12 December 2020

The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM301485D

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23327468

1 reference