(Q36673022)

15 August 2017

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title

Glucocorticoids in multiple sclerosis and experimental autoimmune encephalomyelitis (English)

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15 August 2017

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2

Ralf Gold

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15 August 2017

Holger M Reichardt

1

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15 August 2017

Fred Lühder

series ordinal

3

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15 August 2017

language of work or name

1 reference

1 November 2006

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

15 August 2017

published in

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15 August 2017

volume

6

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15 August 2017

issue

11

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15 August 2017

page(s)

1657-1670

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Primary structure and expression of a functional human glucocorticoid receptor cDNA

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Neuroendocrine regulation of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Different roles for glucocorticoids in thymocyte homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Glucocorticoids and the Th1/Th2 balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Effects of dexamethasone on microglial activation in vivo: selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Regulation of leukocyte-endothelial interactions by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Non-genomic glucocorticoid effects to provide the basis for new drug developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Transcriptional cross-talk, the second mode of steroid hormone receptor action

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

DNA binding of the glucocorticoid receptor is not essential for survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Rapid glucocorticoid effects on immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Animal models for autoimmune demyelinating disorders of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Activated non-neural specific T cells open the blood-brain barrier to circulating antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Blockade of signaling via the very late antigen (VLA-4) and its counterligand vascular cell adhesion molecule-1 (VCAM-1) causes increased T cell apoptosis in experimental autoimmune neuritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term therapy with dexamethasone or cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Endothelial cells of the blood-brain barrier: a target for glucocorticoids and estrogens?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Lack of histamine synthesis and down-regulation of H1 and H2 receptor mRNA levels by dexamethasone in cerebral endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Decreased iNOS synthesis mediates dexamethasone‐induced protection of neurons from inflammatory injury in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Neurotoxicity of soluble macrophage products in vitro--influence of dexamethasone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. The Optic Neuritis Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Stress Hormones, Th1/Th2 patterns, Pro/Anti-inflammatory Cytokines and Susceptibility to Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Cytokines: promoters and dampeners of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Neuroendocrine-immune system interactions and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Steroid hormones in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Differential response of murine CD4+CD25+ and CD4+CD25- T cells to dexamethasone-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Immunomodulatory activities of glucocorticoids: insights from transgenesis and gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Glucocorticoids in the treatment of rheumatic diseases: an update on the mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Apoptosis in the nervous system in experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Novel non-transcriptional mechanisms for estrogen receptor signaling in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

Antiglucocorticosteroid effects suggest why steroid hormone is required for receptors to bind DNA in vivo but not in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.6.11.1657

10.1586/14737175.6.11.1657

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference