(Q36033294)

11 August 2017

1 reference

title

Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis (English)

1 reference

11 August 2017

1 reference

Jan P Tuckermann

1

1 reference

11 August 2017

Anna Kleiman

series ordinal

2

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11 August 2017

Kirsty G McPherson

series ordinal

3

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11 August 2017

Holger M Reichardt

series ordinal

4

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11 August 2017

publication date

1 January 2005

1 reference

Critical Reviews in Clinical Laboratory Sciences

11 August 2017

published in

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11 August 2017

volume

42

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11 August 2017

issue

1

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11 August 2017

page(s)

71-104

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Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions

11 August 2017

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Therapeutic strategies for allergic diseases

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Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia.

21 January 2018

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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

21 January 2018

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Hypercortisolism and obesity

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Molecular genetic analysis of glucocorticoid signaling using the Cre/loxP system

21 January 2018

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The nuclear receptor superfamily: the second decade

21 January 2018

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Steroid hormone receptors: many actors in search of a plot

21 January 2018

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Disassembly of transcriptional regulatory complexes by molecular chaperones

21 January 2018

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Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

21 January 2018

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Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360590888983

Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathway

21 January 2018

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360590888983

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360590888983

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

21 January 2018

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Dynamic behavior of transcription factors on a natural promoter in living cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360590888983

Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Essential role of Swp73p in the function of yeast Swi/Snf complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Regulation of transcription by a protein methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Increasing the complexity of coactivation in nuclear receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid receptor activation of the I kappa B alpha promoter within chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

DNA binding of the glucocorticoid receptor is not essential for survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A negative regulatory region containing a glucocorticosteroid response element (nGRE) in the human interleukin-1beta gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Localization of a negative glucocorticoid response element of the human corticotropin releasing hormone gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Nontranscriptional actions of the glucocorticoid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Rapid glucocorticoid effects on immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Immunobiology of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Immunity or tolerance? That is the question for dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Is maturation required for Langerhans cell migration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Differential effects of corticosteroids during different stages of dendritic cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids increase the synthesis of immunoglobulin E by interleukin 4-stimulated human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Corticosteroids, IgE, and atopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A comparison of the anti-inflammatory properties of intranasal corticosteroids and antihistamines in allergic rhinitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Interleukin 4 is localized to and released by human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Activated mast cells produce interleukin 13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Multifunctional cytokine expression by human mast cells: regulation by T cell membrane contact and glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids inhibit proliferation and adhesion of the IL-3-dependent mast cell line, MC/9, to NIH/3T3 fibroblasts, with an accompanying decrease in IL-3 receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Regulation of leukocyte-endothelial interactions by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The release of a neutrophil chemotactic factor from peritoneal macrophages by endotoxin: inhibition by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Biochemical actions of glucocorticoids on macrophages in culture. Specific inhibition of elastase, collagenase, and plasminogen activator secretion and effects on other metabolic functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Therapeutic concentrations of glucocorticoids suppress the antimicrobial activity of human macrophages without impairing their responsiveness to gamma interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid modulation of human monocyte/macrophage function: control of TNF-alpha secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Macrophage migration inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Cutaneous immunization rapidly activates liver invariant Valpha14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

B cell-dependent T cell responses: IgM antibodies are required to elicit contact sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Apoptosis in the development and maintenance of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The CD95 type I/type II model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Caspase-independent cell death in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Disruption of glucocorticoid receptor exon 2 yields a ligand-responsive C-terminal fragment that regulates gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid signalling--multiple variations of a common theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Transcriptional cross-talk, the second mode of steroid hormone receptor action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Critical function of T cell death-associated gene 8 in glucocorticoid-induced thymocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Resistance of single-positive thymocytes to glucocorticoid-induced apoptosis is mediated by CD28 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Hydrogen peroxide as second messenger in lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Recent insights into the mechanism of glucocorticosteroid-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Activation and inhibition of lymphocytes by costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Impaired negative selection in CD28-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids and thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

In thymic selection, peptide diversity gives and takes away

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

T-cell development and the CD4-CD8 lineage decision

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Glucocorticoids down‐regulate dendritic cell function in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

Steroids inhibit uptake and/or processing but not presentation of antigen by airway dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360590888983

10.1080/10408360590888983

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference