(Q36689595)

15 August 2017

1 reference

title

On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies (English)

1 reference

genome-wide association study

15 August 2017

main subject

0 references

3

Marta Gwinn

1 reference

15 August 2017

1

Muin J Khoury

1 reference

15 August 2017

2

Julian Little

1 reference

15 August 2017

John P A Ioannidis

4

1 reference

15 August 2017

publication date

20 December 2006

1 reference

International Journal of Epidemiology

15 August 2017

published in

1 reference

15 August 2017

volume

36

1 reference

15 August 2017

issue

2

1 reference

15 August 2017

page(s)

439-445

1 reference

Welcome to the genomic era.

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Shaking the tree: mapping complex disease genes with linkage disequilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

A haplotype map of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Evaluating coverage of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

A common variant associated with prostate cancer in European and African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

A polygenic basis for late-onset disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

MULTIFACTORIAL GENETICSUNDERSTANDING QUANTITATIVE GENETIC VARIATION

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

A common genetic variant is associated with adult and childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

High "population attributable fraction" for coronary heart disease mortality among relatives in monogenic familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Causation and causal inference in epidemiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

How many genes underlie the occurrence of common complex diseases in the population?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Genome-wide strategies for detecting multiple loci that influence complex diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Why most published research findings are false

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Genetic associations: false or true?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Genetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Prospects and pitfalls in whole genome association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Integrating epidemiology and genetic association: the challenge of gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Obstacles and opportunities in meta-analysis of genetic association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Insulin-like growth factor I, insulin-like growth factor binding protein 3, and urologic measures of benign prostatic hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Genomic epidemiology of complex disease: the need for an electronic evidence-based approach to research synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Preclinical assessment of HIV vaccines and microbicides by repeated low-dose virus challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Population structure, differential bias and genomic control in a large-scale, case-control association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

The emergence of epidemiology in the genomics age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Gearing up for genome-wide gene-association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

A network of investigator networks in human genome epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

US ponders unlocking the gates to prisoner research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Assessing the function of genetic variants in candidate gene association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

How frequent is altered gene expression among susceptibility genes to human complex disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Epidemiologic evaluation of screening for risk factors: application to genetic screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Do we need genomic research for the prevention of common diseases with environmental causes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Impact of Violations and Deviations in Hardy-Weinberg Equilibrium on Postulated Gene-Disease Associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

Will Genetics Revolutionize Medicine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

What makes a good genetic association study?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FIJE%2FDYL253

21 January 2018

Identifiers

DOI

10.1093/IJE/DYL253

1 reference

15 August 2017

1 reference