(Q36693131)

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Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer

scientific article published on 29 January 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer (English)

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PMC publication ID

15 August 2017

triple-negative breast cancer

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John A Cidlowski

4

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11 June 2020

Tiffany N Seagroves

8

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11 June 2020

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Carol A Lange

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11 June 2020

Tarah M. Regan Anderson

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Tarah M Regan Anderson

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11 June 2020

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Shi Hong Ma

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11 June 2020

Ganesh V Raj

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11 June 2020

Taylor M Helle

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11 June 2020

Todd P Knutson

6

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11 June 2020

Raisa I Krutilina

7

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11 June 2020

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29 January 2016

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15 August 2017

Cancer Research

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11 June 2020

76

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11 June 2020

6

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11 June 2020

1653-1663

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11 June 2020

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11 June 2022

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Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases

1 reference

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Minireview: Deciphering the Cellular Functions of PELP1

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Novel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells

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ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

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30 September 2017

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

1 reference

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30 September 2017

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes

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30 September 2017

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.

1 reference

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Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

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Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition

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30 September 2017

Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression

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30 September 2017

Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR

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Ligand-independent phosphorylation of the glucocorticoid receptor integrates cellular stress pathways with nuclear receptor signaling

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30 September 2017

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.

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30 September 2017

Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer

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30 September 2017

Brk/PTK6 signaling in normal and cancer cell models

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Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells

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PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival

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Effects of corticosteroid use on treatment of solid tumours

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BRK tyrosine kinase expression in a high proportion of human breast carcinomas

1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-15-2510

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26825173%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PMC publication ID

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Europe PubMed Central

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11 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26825173%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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