(Q36704473)

15 August 2017

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title

Plasmid-based gene therapy of diabetes mellitus (English)

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15 August 2017

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Prud'homme GJ

1

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15 August 2017

Draghia-Akli R

series ordinal

2

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15 August 2017

Wang Q

series ordinal

3

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15 August 2017

11 January 2007

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15 August 2017

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15 August 2017

14

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15 August 2017

7

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15 August 2017

553-564

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302907

15 August 2017

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cites work

Direct gene transfer into mouse muscle in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Immunotherapeutic gene transfer into muscle

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

DNA electrotransfer: its principles and an updated review of its therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Plasmid-mediated muscle-targeted gene therapy for circulating therapeutic protein replacement: a tale of the tortoise and the hare?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

In vivo electroporation for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Plasmid DNA entry into postmitotic nuclei of primary rat myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Immunotherapeutic uses of CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

CpG motifs in bacterial DNA and their immune effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Altering immune tolerance therapeutically: the power of negative thinking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

The NOD mouse: a model of immune dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Disruption of immunological tolerance: role of AIRE gene in autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

AIRE and APECED: molecular insights into an autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Regulatory T cells in human disease and their potential for therapeutic manipulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

21 January 2018

FOXP3: of mice and men.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Type I regulatory T cells in autoimmunity and inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Prevention of autoimmune diabetes by DNA vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

DNA vaccination against tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

DNA vaccines to attack cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Strategies for improved formulation and delivery of DNA vaccines to veterinary target species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Differential immune response to B:9-23 insulin 1 and insulin 2 peptides in animal models of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Immunoinhibitory DNA vaccine protects against autoimmune diabetes through cDNA encoding a selective CTLA-4 (CD152) ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Gene therapy of streptozotocin-induced diabetes by intramuscular delivery of modified preproinsulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Lower limb amputations in Southern Finland in 2000 and trends up to 2001.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a double-blind randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Gene transfer into muscle by electroporation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Protective regulatory T cell generation in autoimmune diabetes by DNA covaccination with islet antigens and a selective CTLA-4 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Gene Electrotransfer Results in a High-Level Transduction of Rat Skeletal Muscle and Corrects Anemia of Renal Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

Nonclinical toxicology in support of licensure of gene therapies. Arlington, VA, USA, March 13-14, 2003

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Highly efficient constant-current electroporation increases in vivo plasmid expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Plasmid DNA vaccines: tissue distribution and effects of DNA sequence, adjuvants and delivery method on integration into host DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Plasmid DNA vaccines: investigation of integration into host cellular DNA following intramuscular injection in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Lessons on autoimmune diabetes from animal models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

DNA immunization to prevent autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

DNA vaccination with glutamic acid decarboxylase (GAD) generates a strong humoral immune response in BALB/c, C57BL/6, and in diabetes-prone NOD mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Regulatory cytokine production stimulated by DNA vaccination against an altered form of glutamic acid decarboxylase 65 in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Pro-apoptotic DNA vaccination ameliorates new onset of autoimmune diabetes in NOD mice and induces foxp3+ regulatory T cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

The management and outcome of critical limb ischaemia in diabetic patients: results of a national survey. Audit Committee of the Vascular Surgical Society of Great Britain and Ireland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Decreasing incidence of major amputations in people with diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Survival in patients with chronic lower extremity ischemia: a risk factor analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Erythropoietin secretion and physiological effect in mouse after intramuscular plasmid DNA electrotransfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Electroporation improves the efficacy of DNA vaccines in large animals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302907

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302907

1 reference

release_kfl2kokftjegflkqhiwsqghdti

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kfl2kokftjegflkqhiwsqghdti

24 November 2022

mapped directly with Wikidata item

1 reference