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Negative regulation of the RalGAP complex by 14-3-3.
scientific article published on 5 February 2013
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PMC publication ID
3610998
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23 February 2020
title
Negative regulation of the RalGAP complex by 14-3-3
(English)
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PMC publication ID
3610998
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23 February 2020
author
Alan R. Saltiel
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5
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23 February 2020
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Dara Leto
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3610998
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23 February 2020
Maeran Uhm
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2
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23 February 2020
Anja Williams
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3
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23 February 2020
Xiao-wei Chen
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4
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23 February 2020
language of work or name
English
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5 February 2013
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3610998
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23 February 2020
published in
Journal of Biological Chemistry
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23 February 2020
volume
288
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23 February 2020
issue
13
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23 February 2020
page(s)
9272-9283
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23 February 2020
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Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c
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Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation
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Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.
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PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.
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Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
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The Rgr oncogene (homologous to RalGDS) induces transformation and gene expression by activating Ras, Ral and Rho mediated pathways
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Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral
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30 September 2017
The small GTPase RalA targets filamin to induce filopodia
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Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity
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30 September 2017
A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.
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28 June 2018
Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation
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28 June 2018
Characterization of a GTPase-activating protein for the Ras-related Ral protein.
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28 June 2018
Ral's engagement with the exocyst: breaking up is hard to do.
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5 September 2018
PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin.
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5 September 2018
Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia.
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5 September 2018
p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
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5 September 2018
Tiam1 is recruited to β1-integrin complexes by 14-3-3ζ where it mediates integrin-induced Rac1 activation and motility
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12 December 2020
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Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M112.426106
1 reference
stated in
Europe PubMed Central
PMC publication ID
3610998
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
PMC publication ID
3610998
1 reference
stated in
Europe PubMed Central
PMC publication ID
3610998
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
PubMed publication ID
23386617
1 reference
stated in
Europe PubMed Central
PMC publication ID
3610998
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23386617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
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