(Q36744200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18487202%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Differences in a conformational equilibrium distinguish catalysis by the endothelial and neuronal nitric-oxide synthase flavoproteins (English)

1 reference

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7 January 2020

0 references

4

1 reference

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7 January 2020

author name string

Robielyn P Ilagan

1

1 reference

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7 January 2020

Mauro Tiso

2

1 reference

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7 January 2020

David W Konas

3

1 reference

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7 January 2020

Deborah Durra

5

1 reference

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7 January 2020

Russ Hille

6

1 reference

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7 January 2020

Dennis J Stuehr

7

1 reference

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7 January 2020

language of work or name

English

0 references

publication date

16 May 2008

1 reference

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Journal of Biological Chemistry

7 January 2020

published in

1 reference

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7 January 2020

volume

283

1 reference

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7 January 2020

issue

28

1 reference

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7 January 2020

page(s)

19603-19615

1 reference

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A connecting hinge represses the activity of endothelial nitric oxide synthase.

7 January 2020

cites work

1 reference

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Direct measurement by laser flash photolysis of intraprotein electron transfer in a rat neuronal nitric oxide synthase

29 September 2017

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Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking

29 September 2017

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Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein

29 September 2017

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29 September 2017

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Involvement of NADPH in the interaction between heme oxygenase-1 and cytochrome P450 reductase

29 September 2017

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Update on mechanism and catalytic regulation in the NO synthases.

29 September 2017

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29 September 2017

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Nitric-oxide synthase (NOS) reductase domain models suggest a new control element in endothelial NOS that attenuates calmodulin-dependent activity

29 September 2017

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Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation

29 September 2017

1 reference

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Electron transfer in human cytochrome P450 reductase.

29 September 2017

1 reference

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Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains

29 September 2017

1 reference

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Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1

29 September 2017

1 reference

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A conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificity

29 September 2017

1 reference

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P450 BM3: the very model of a modern flavocytochrome

29 September 2017

1 reference

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Intrinsic and extrinsic modulation of nitric oxide synthase activity.

29 September 2017

1 reference

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Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?

29 September 2017

1 reference

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Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase

29 September 2017

1 reference

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NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

29 September 2017

1 reference

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Determination of the redox properties of human NADPH-cytochrome P450 reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Potentiometric analysis of the flavin cofactors of neuronal nitric oxide synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

A productive NADP+ binding mode of ferredoxin-NADP + reductase revealed by protein engineering and crystallographic studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Mammalian nitric oxide synthases

29 September 2017

1 reference

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Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution

29 September 2017

1 reference

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Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase

29 September 2017

1 reference

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Characterization of the reductase domain of rat neuronal nitric oxide synthase generated in the methylotrophic yeast Pichia pastoris. Calmodulin response is complete within the reductase domain itself

29 September 2017

1 reference

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Endothelial nitric-oxide synthase. Evidence for bidomain structure and successful reconstitution of catalytic activity from two separate domains generated by a baculovirus expression system

29 September 2017

1 reference

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Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes

29 September 2017

1 reference

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Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer

29 September 2017

1 reference

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Location and magnetic relaxation properties of the stable tyrosine radical in photosystem II.

29 September 2017

1 reference

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Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element

29 September 2017

1 reference

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Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.

28 June 2018

1 reference

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Redox control of the catalytic cycle of flavocytochrome P-450 BM3.

28 June 2018

1 reference

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An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase

28 June 2018

1 reference

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Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.

28 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Neuronal nitric-oxide synthase interaction with calmodulin-troponin C chimeras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Calmodulin-dependent regulation of mammalian nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Versatile regulation of neuronal nitric oxide synthase by specific regions of its C-terminal tail.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Electron transfer is activated by calmodulin in the flavin domain of human neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Stopped-flow kinetic studies of electron transfer in the reductase domain of neuronal nitric oxide synthase: re-evaluation of the kinetic mechanism reveals new enzyme intermediates and variation with cytochrome P450 reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human endothelial NOS reductase domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Global effects of the energetics of coenzyme binding: NADPH controls the protein interaction properties of human cytochrome P450 reductase.

21 January 2018

1 reference

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Relaxation kinetics of cytochrome P450 reductase: internal electron transfer is limited by conformational change and regulated by coenzyme binding.

21 January 2018

1 reference

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Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues

21 January 2018

1 reference

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Redox properties of the isolated flavin mononucleotide- and flavin adenine dinucleotide-binding domains of neuronal nitric oxide synthase

21 January 2018

1 reference

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Reductase domain of Drosophila melanogaster nitric-oxide synthase: redox transformations, regulation, and similarity to mammalian homologues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

A heat shock protein 90 binding domain in endothelial nitric-oxide synthase influences enzyme function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Electron transfer by neuronal nitric-oxide synthase is regulated by concerted interaction of calmodulin and two intrinsic regulatory elements

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443662

Competition between C-terminal Tyrosine and Nicotinamide Modulates Pyridine Nucleotide Affinity and Specificity in Plant Ferredoxin-NADP+Reductase

20 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802914200

Azo reduction of methyl red by neuronal nitric oxide synthase: the important role of FMN in catalysis

21 January 2018

1 reference

12 December 2020

Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase

1 reference

12 December 2020

Conformational and Thermodynamic Control of Electron Transfer in Neuronal Nitric Oxide Synthase†

1 reference

12 December 2020

Calmodulin activates intramolecular electron transfer between the two flavins of neuronal nitric oxide synthase flavin domain

1 reference

12 December 2020

Oxidation-reduction potentials of cytochromes in mitochondria

1 reference

12 December 2020

Role of reductase domain cluster 1 acidic residues in neuronal nitric-oxide synthase. Characterization of the FMN-FREE enzyme

1 reference

12 December 2020

The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M802914200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18487202%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18487202%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

18487202

1 reference