(Q36752770)

16 August 2017

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title

The beginning of the end: death signaling in early involution (English)

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16 August 2017

Fiona O Baxter

1

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16 August 2017

Kevin Neoh

series ordinal

2

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16 August 2017

Maxine C Tevendale

series ordinal

3

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16 August 2017

publication date

1 March 2007

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Journal of Mammary Gland Biology and Neoplasia

16 August 2017

published in

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16 August 2017

volume

12

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16 August 2017

issue

1

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16 August 2017

page(s)

3-13

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Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis

16 August 2017

cites work

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12 December 2020

The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.

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12 December 2020

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

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12 December 2020

Induction of NF-kappaB by the Akt/PKB kinase

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12 December 2020

How many ways to die? How many different models of cell death?

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12 December 2020

Apoptosis and mammary gland involution: reviewing the process

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12 December 2020

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

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12 December 2020

Extracellular matrix regulates expression of the TGF-beta 1 gene

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12 December 2020

Protein kinase A and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells

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12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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12 December 2020

Identification of c-MYC as a target of the APC pathway

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12 December 2020

Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

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12 December 2020

Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release

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12 December 2020

Hormonal control of insulin-like growth factor-binding protein-5 production in the involuting mammary gland of the rat

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12 December 2020

Essential role of STAT3 in cytokine-driven NF-kappaB-mediated serum amyloid A gene expression.

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12 December 2020

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

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12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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12 December 2020

IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cells

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12 December 2020

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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12 December 2020

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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12 December 2020

Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B

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12 December 2020

TGF-beta in mammary gland development and breast cancer.

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12 December 2020

Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation

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12 December 2020

Synthesis and function of 3-phosphorylated inositol lipids

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12 December 2020

Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

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12 December 2020

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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12 December 2020

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

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12 December 2020

Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling

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12 December 2020

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

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12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

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12 December 2020

Phosphoinositide 3-kinase signalling--which way to target?

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12 December 2020

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

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12 December 2020

Regulation of Smad signalling by protein associations and signalling crosstalk

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12 December 2020

NF-kappaB inhibits apoptosis in murine mammary epithelia

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12 December 2020

Cell-matrix interactions during development and apoptosis of the mouse mammary gland in vivo.

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12 December 2020

Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

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12 December 2020

Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

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12 December 2020

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

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12 December 2020

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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12 December 2020

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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12 December 2020

Apoptosis regulation in the mammary gland

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12 December 2020

TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

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12 December 2020

Differential expression of the TGF-beta isoforms in embryogenesis suggests specific roles in developing and adult tissues

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12 December 2020

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis

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12 December 2020

Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase

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12 December 2020

Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3

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12 December 2020

Role of DDC-4/sFRP-4, a secreted frizzled-related protein, at the onset of apoptosis in mammary involution.

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12 December 2020

Regulation of cell death protease caspase-9 by phosphorylation

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12 December 2020

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

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12 December 2020

Signaling pathways in mammary gland development.

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12 December 2020

The biochemistry of apoptosis

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12 December 2020

Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution.

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12 December 2020

Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition

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12 December 2020

Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution

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12 December 2020

Smads as transcriptional co-modulators

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12 December 2020

Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model

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12 December 2020

Mechanisms of TGF-beta-mediated apoptosis

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12 December 2020

Delayed mammary gland involution in MMTV-AKT1 transgenic mice

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12 December 2020

Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression

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12 December 2020

Mammary gland involution is delayed by activated Akt in transgenic mice.

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12 December 2020

Leukemia inhibitory factor induces apoptosis of the mammary epithelial cells and participates in mouse mammary gland involution.

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12 December 2020

An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism

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12 December 2020

The mitochondrial ARTS protein promotes apoptosis through targeting XIAP

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12 December 2020

The TGF beta receptor activation process: an inhibitor- to substrate-binding switch

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12 December 2020

The transforming growth factors beta in development and functional differentiation of the mouse mammary gland.

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12 December 2020

Inhibition of mammary epithelial apoptosis and sustained phosphorylation of Akt/PKB in MMTV-IGF-II transgenic mice

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12 December 2020

Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8

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12 December 2020

Apoptosis in normal and neoplastic mammary gland development

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12 December 2020

Activation of NF-kappaB p50/p65 is regulated in the developing mammary gland and inhibits STAT5-mediated beta-casein gene expression

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12 December 2020

Mammary gland-specific nuclear factor activity is positively regulated by lactogenic hormones and negatively by milk stasis

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12 December 2020

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

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12 December 2020

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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12 December 2020

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

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12 December 2020

The logic of TGFbeta signaling.

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12 December 2020

Glucocorticoid and progesterone inhibit involution and programmed cell death in the mouse mammary gland

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12 December 2020

Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta.

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12 December 2020

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase

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12 December 2020

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

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12 December 2020

Mfge8 is critical for mammary gland remodeling during involution

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12 December 2020

A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland

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12 December 2020

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

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12 December 2020

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

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12 December 2020

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

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12 December 2020

C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution

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12 December 2020

Roles of Fas and Fas ligand during mammary gland remodeling

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12 December 2020

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

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12 December 2020

10.1007/S10911-007-9033-9

Identifiers

DOI

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16 August 2017

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