(Q36753352)

16 August 2017

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability (English)

1 reference

16 August 2017

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4

Fersht AR

1 reference

16 August 2017

Nikolova PV

1

1 reference

16 August 2017

Henckel J

series ordinal

2

1 reference

16 August 2017

Lane DP

series ordinal

3

1 reference

16 August 2017

language of work or name

English

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publication date

1 December 1998

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

95

1 reference

16 August 2017

25

1 reference

16 August 2017

14675-14680

1 reference

The CCP4 suite: programs for protein crystallography

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Thermodynamic stability of wild-type and mutant p53 core domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Regulation of p53 stability by Mdm2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Structural aspects of the p53 protein in relation to gene evolution: a second look.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Design and structural analysis of an engineered thermostable chicken lysozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

How loops, beta sheets, and alpha helices help us to understand p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

DNA damage, p53 and anticancer therapies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Cancer. p53, guardian of the genome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Additivity of mutational effects in proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Keeping an old friend under control: regulation of p53 stability

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

Intercellular delivery of functional p53 by the herpesvirus protein VP22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

Sequence statistics reliably predict stabilizing mutations in a protein domain

20 October 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24508

20 October 2018

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

Structure-based rescue of common tumor-derived p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.25.14675

21 January 2018

Identifiers

DOI

10.1073/PNAS.95.25.14675

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

9843948

1 reference