(Q36757044)

16 August 2017

Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease (English)

1 reference

16 August 2017

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Jiun-Tsai Lin

1

1 reference

16 August 2017

Wei-Cheng Chang

2

1 reference

16 August 2017

Hui-Mei Chen

3

1 reference

16 August 2017

Hsing-Lin Lai

4

1 reference

16 August 2017

Chih-Yeh Chen

5

1 reference

16 August 2017

Mi-Hua Tao

6

1 reference

16 August 2017

Yijuang Chern

7

1 reference

16 August 2017

language of work or name

English

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publication date

28 December 2012

1 reference

Molecular and Cellular Biology

16 August 2017

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16 August 2017

33

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16 August 2017

5

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16 August 2017

1073-1084

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describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3623082/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Gastrodia elata prevents huntingtin aggregations through activation of the adenosine A₂A receptor and ubiquitin proteasome system

29 September 2017

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A new drug design targeting the adenosinergic system for Huntington's disease

29 September 2017

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29 September 2017

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Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease

29 September 2017

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Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington’s Disease: Exercise, Adenosine Receptors and Ampakines

29 September 2017

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Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

29 September 2017

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Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments

29 September 2017

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29 September 2017

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Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines

29 September 2017

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Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases

29 September 2017

1 reference

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The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system

29 September 2017

1 reference

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The ubiquitin-proteasome reporter GFPu does not accumulate in neurons of the R6/2 transgenic mouse model of Huntington's disease

29 September 2017

1 reference

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Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9.

29 September 2017

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Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

29 September 2017

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Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process

29 September 2017

1 reference

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A critical evaluation of adenosine A2A receptors as potentially "druggable" targets in Huntington's disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice

29 September 2017

1 reference

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Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6

29 September 2017

1 reference

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Proteasomes: machines for all reasons

29 September 2017

1 reference

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Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease

29 September 2017

1 reference

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The corticostriatal pathway in Huntington's disease

29 September 2017

1 reference

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CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

O-GlcNAc modification is an endogenous inhibitor of the proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Secular trends in mortality associated with bloodstream infections in 4268 patients hospitalized in a cancer referral center between 1975 and 1989.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease

29 September 2017

1 reference

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The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution

29 September 2017

1 reference

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ST14A cells have properties of a medium-size spiny neuron.

29 September 2017

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

29 September 2017

1 reference

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Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity

29 September 2017

1 reference

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Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells.

29 September 2017

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

29 September 2017

1 reference

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Huntington's disease. Pathogenesis and management

29 September 2017

1 reference

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Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

29 September 2017

1 reference

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The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Activity-dependent growth of new dendritic spines is regulated by the proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Expression of type VI adenylyl cyclase in the central nervous system: implication for a potential regulator of multiple signals in different neurotransmitter systems

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

A deconvolution method to improve automated 3D-analysis of dendritic spines: application to a mouse model of Huntington's disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

A2A receptor knockout worsens survival and motor behaviour in a transgenic mouse model of Huntington's disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Global changes to the ubiquitin system in Huntington's disease.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Opposite effects of the A2A receptor agonist CGS21680 in the striatum of Huntington's disease versus wild-type mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

A proteasome-sensitive connection between PSD-95 and GluR1 endocytosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

A transgenic mouse model of the ubiquitin/proteasome system

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3623082

5 September 2018

Identifiers

DOI

10.1128/MCB.01434-12

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23275441

1 reference