(Q36758006)

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Peroxisome proliferator-activated receptor alpha protects renal tubular cells from gentamicin-induced apoptosis via upregulating Na(+)/H(+) exchanger NHE1.

scientific article published on 23 November 2015

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scholarly article

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1 March 2020

Peroxisome Proliferator-Activated Receptor α Protects Renal Tubular Cells from Gentamicin-Induced Apoptosis via Upregulating Na+/H+ Exchanger NHE1 (English)

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1 March 2020

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1 March 2020

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Cheng-Hsien Chen

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Tso-Hsiao Chen

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1 March 2020

Jia-Rung Chen

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Li-Yu Hong

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Cai-Mei Zheng

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1 March 2020

I-Jen Chiu

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1 March 2020

Yuh-Feng Lin

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Yung-Ho Hsu

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23 November 2015

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1 March 2020

Molecular Medicine

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1 March 2020

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886-889

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1 March 2020

copyright license

Creative Commons Attribution 4.0 International

1 January 2015

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April 2022 Public Data File from Crossref

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https://scigraph.springernature.com/pub.10.2119/molmed.2015.00196

0 references

Na+-H+ exchanger-1 (NHE1) regulation in kidney proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4818255

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Intracellular Acid-extruding regulators and the effect of lipopolysaccharide in cultured human renal artery smooth muscle cells

1 reference

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Regulation of energy metabolism by long-chain fatty acids

1 reference

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29 September 2017

Role of the peroxisome proliferator-activated receptors (PPAR)-α, β/δ and γ triad in regulation of reactive oxygen species signaling in brain

1 reference

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29 September 2017

Urotensin II exerts antiapoptotic effect on NRK-52E cells through prostacyclin-mediated peroxisome proliferator-activated receptor alpha and Akt activation

1 reference

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29 September 2017

Animal models of acute renal failure

1 reference

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Far-infrared therapy induces the nuclear translocation of PLZF which inhibits VEGF-induced proliferation in human umbilical vein endothelial cells

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Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

1 reference

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29 September 2017

Experimental gentamicin nephrotoxicity and agents that modify it: a mini-review of recent research

1 reference

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29 September 2017

An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin

1 reference

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29 September 2017

Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1.

1 reference

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29 September 2017

Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic protein

1 reference

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29 September 2017

Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells

1 reference

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29 September 2017

Identification of a functional peroxisome proliferator-activated receptor (PPAR) response element (PPRE) in the human apolipoprotein A-IV gene

1 reference

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29 September 2017

Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung

1 reference

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29 September 2017

Regulation of cell survival by Na+/H+ exchanger-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4818255

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Regulation of epithelial sodium transport by promyelocytic leukemia zinc finger protein

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29 September 2017

Peroxisomal proliferator-activated receptor-alpha protects renal tubular cells from doxorubicin-induced apoptosis

1 reference

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A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein

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29 September 2017

Gentamicin causes apoptosis at low concentrations in renal LLC-PK1 cells subjected to electroporation

1 reference

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29 September 2017

Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.

1 reference

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29 September 2017

Alterations of intracellular pH homeostasis in apoptosis: origins and roles

1 reference

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29 September 2017

Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level

1 reference

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Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection.

1 reference

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29 September 2017

Apoptosis induced by Na+/H+ antiport inhibition activates the LEI/L-DNase II pathway

1 reference

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PPAR alpha and the regulation of cell division and apoptosis.

1 reference

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29 September 2017

Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger

1 reference

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Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

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29 September 2017

Na+/H+ exchangers of mammalian cells.

1 reference

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1 reference

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28 June 2018

Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPARalpha-dependent pathway

1 reference

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Fibrate prevents cisplatin-induced proximal tubule cell death

1 reference

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A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

1 reference

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4 December 2018

Identifiers

10.2119/MOLMED.2015.00196

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1 March 2020

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1 March 2020

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Europe PubMed Central

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1 March 2020

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