(Q36772394)

16 August 2017

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title

Biosynthesis of aminocyclitol-aminoglycoside antibiotics and related compounds (English)

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16 August 2017

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Patricia M Flatt

1

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PubMed ID

17390001

16 August 2017

Taifo Mahmud

series ordinal

2

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16 August 2017

21 December 2006

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16 August 2017

Natural Product Reports

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16 August 2017

24

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16 August 2017

2

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16 August 2017

358-392

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In vitro activities of spectinomycin and comparator agents against Pasteurella multocida and Mannheimia haemolytica from respiratory tract infections of cattle

16 August 2017

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Studies on the biosynthesis of antibiotics

21 January 2018

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The C7N aminocyclitol family of natural products.

21 January 2018

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Diversification and evolution of L‐myo‐inositol 1‐phosphate synthase1

21 January 2018

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The crystal structure and mechanism of 1-L-myo-inositol- 1-phosphate synthase

21 January 2018

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Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis

21 January 2018

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Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis

21 January 2018

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Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism

21 January 2018

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Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity

21 January 2018

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Gene cluster for streptomycin biosynthesis in Streptomyces griseus: analysis of a central region including the major resistance gene.

21 January 2018

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Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes.

21 January 2018

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The StrQ protein encoded in the gene cluster for 5'-hydroxystreptomycin of Streptomyces glaucescens GLA.0 is a alpha-D-glucose-1-phosphate cytidylyltransferase (CDP-D-glucose synthase).

21 January 2018

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Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus.

21 January 2018

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An AfsK/AfsR system involved in the response of aerial mycelium formation to glucose in Streptomyces griseus.

21 January 2018

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The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A-factor receptor.

21 January 2018

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S-adenosylmethionine activates adpA transcription and promotes streptomycin biosynthesis in Streptomyces griseus.

21 January 2018

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Genetics of streptomycin production in Streptomyces griseus: nucleotide sequence of five genes, strFGHIK, including a phosphatase gene.

21 January 2018

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Crystal structure of L-arginine:inosamine-phosphate amidinotransferase StrB1 from Streptomyces griseus: an enzyme involved in streptomycin biosynthesis

21 January 2018

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Genetics of streptomycin production in Streptomyces griseus: molecular structure and putative function of genes strELMB2N

21 January 2018

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Possible evolutionary relationships between streptomycin and bluensomycin biosynthetic pathways: detection of novel inositol kinase and O-carbamoyltransferase activities

21 January 2018

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Isolation and characterization of bluensomycin biosynthetic genes from Streptomyces bluensis

21 January 2018

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An efficient approach for cloning the dNDP-glucose synthase gene from actinomycetes and its application in Streptomyces spectabilis, a spectinomycin producer

21 January 2018

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A novel, highly efficient gene-cloning system in Micromonospora applied to the genetic analysis of fortimicin biosynthesis

21 January 2018

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Biosynthetic origin of hygromycin A.

21 January 2018

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Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus

21 January 2018

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2-Deoxystreptamine: central scaffold of aminoglycoside antibiotics

21 January 2018

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Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

21 January 2018

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Interaction of antibiotics with functional sites in 16S ribosomal RNA

21 January 2018

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Modulation of RNA function by aminoglycoside antibiotics

21 January 2018

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The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine

21 January 2018

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An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius

21 January 2018

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A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster

21 January 2018

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Isolation and characterization of the tobramycin biosynthetic gene cluster from Streptomyces tenebrarius

21 January 2018

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Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics

21 January 2018

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Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

21 January 2018

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Active site mapping of 2-deoxy-scyllo-inosose synthase, the key starter enzyme for the biosynthesis of 2-deoxystreptamine. Mechanism-based inhibition and identification of lysine-141 as the entrapped nucleophile

21 January 2018

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Expression of 2-deoxy-scyllo-inosose synthase (kanA) from kanamycin gene cluster in Streptomyces lividans.

21 January 2018

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Biophysical and kinetic analysis of wild-type and site-directed mutants of the isolated and native dehydroquinate synthase domain of the AROM protein

21 January 2018

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Crystallization and X-ray analysis of 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics.

21 January 2018

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Significance of the 20-kDa subunit of heterodimeric 2-deoxy-scyllo-inosose synthase for the biosynthesis of butirosin antibiotics in Bacillus circulans

21 January 2018

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Biosynthesis of butirosin in Bacillus circulans NRRL B3312: identification by sequence analysis and insertional mutagenesis of the butB gene involved in antibiotic production

21 January 2018

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Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine

21 January 2018

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Stereochemical recognition of doubly functional aminotransferase in 2-deoxystreptamine biosynthesis.

21 January 2018

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A new family of glucose-1-phosphate/glucosamine-1-phosphate nucleotidylyltransferase in the biosynthetic pathways for antibiotics.

21 January 2018

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Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway

21 January 2018

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Identification and functional analysis of dTDP-glucose-4,6-dehydratase gene and its linked gene cluster in an aminoglycoside antibiotics producer of Streptomyces tenebrarius H6.

21 January 2018

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Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus

21 January 2018

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Biosynthesis of the validamycins: identification of intermediates in the biosynthesis of validamycin A by Streptomyces hygroscopicus var. limoneus.

21 January 2018

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The biosynthesis of acarbose and validamycin.

21 January 2018

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The AcbC protein from Actinoplanes species is a C7-cyclitol synthase related to 3-dehydroquinate synthases and is involved in the biosynthesis of the alpha-glucosidase inhibitor acarbose.

21 January 2018

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Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A.

21 January 2018

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Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008

21 January 2018

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Genetic localization and heterologous expression of validamycin biosynthetic gene cluster isolated from Streptomyces hygroscopicus var. limoneus KCCM 11405 (IFO 12704).

21 January 2018

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Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.

21 January 2018

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The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase

21 January 2018

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Biosynthetic studies on the alpha-glucosidase inhibitor acarbose: the chemical synthesis of isotopically labeled 2-epi-5-epi-valiolone analogs.

21 January 2018

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Biotechnology and molecular biology of the alpha-glucosidase inhibitor acarbose

21 January 2018

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Identification of genes necessary for jinggangmycin biosynthesis from Streptomyces hygroscopicus 10-22.

21 January 2018

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A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine

21 January 2018

1 reference

Prokaryotic triterpenoids. A novel hopanoid from the ethanol-producing bacterium Zymomonas mobilis

21 January 2018

1 reference

Prokaryotic hopanoids: the biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose

21 January 2018

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Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine

21 January 2018

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Transfer and isomerization of the ribose moiety of AdoMet during the biosynthesis of queuosine tRNAs, a new unique reaction catalyzed by the QueA protein from Escherichia coli

21 January 2018

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Kinetic Mechanism of the tRNA-Modifying Enzyme S-Adenosylmethionine:tRNA Ribosyltransferase-Isomerase (QueA)

21 January 2018

1 reference

Mechanistic studies of the tRNA-modifying enzyme QueA: a chemical imperative for the use of AdoMet as a "ribosyl" donor

21 January 2018

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tRNA modification by S-adenosylmethionine:tRNA ribosyltransferase-isomerase. Assay development and characterization of the recombinant enzyme

21 January 2018

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Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts

21 January 2018

1 reference

A gene (pks2) encoding a putative 6-methylsalicylic acid synthase from Glarea lozoyensis

21 January 2018

1 reference

Production of 6-methylsalicylic acid by expression of a fungal polyketide synthase activates disease resistance in tobacco

21 January 2018

1 reference

Natural products derived from unusual variants of the shikimate pathway

21 January 2018

1 reference

Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.

21 January 2018

1 reference

From ergot to ansamycins-45 years in biosynthesis

21 January 2018

1 reference

Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.

21 January 2018

1 reference

Biosynthetic studies on the cyclopentane ring formation of allosamizoline, an aminocyclitol component of the chitinase inhibitor allosamidin

21 January 2018

1 reference

New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium

21 January 2018

1 reference

Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.

21 January 2018

1 reference

Composite hopanoid biosynthesis in Zymomonas mobilis: N-acetyl-D-glucosamine as precursor for the cyclopentane ring linked to bacteriohopanetetrol

21 January 2018

1 reference

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

21 January 2018

1 reference

Combinatorial biosynthesis of reduced polyketides

21 January 2018

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Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides

21 January 2018

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Formation of unusual sugars: mechanistic studies and biosynthetic applications

21 January 2018

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Identification of aminotransferase genes for biosynthesis of aminoglycoside antibiotics from soil DNA.

21 January 2018

1 reference

Structural analysis of Saccharomyces cerevisiae myo-inositol phosphate synthase

21 January 2018

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The biosynthesis of carbocyclic nucleosides

21 January 2018

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Revised pathway for the biosynthesis of aristeromycin and neplanocin A from D-glucose in Streptomyces citricolor

21 January 2018

1 reference

Gene cluster in Micromonospora echinospora ATCC15835 for the biosynthesis of the gentamicin C complex

21 January 2018

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.57.436

The kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus.

12 April 2024

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.57.351

kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster.

12 April 2024

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.1053

Butirosin-biosynthetic Gene Cluster from Bacillus circulans.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.53.1158

A 7.6kb DNA region from Streptomyces kasugaensis M338-M1 includes some genes responsible for kasugamycin biosynthesis.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.51.341

Biosynthetic studies on the alpha-glucosidase inhibitor acarbose in Actinoplanes sp.: glutamate is the primary source of the nitrogen in acarbose

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.51.225

Biosynthetic studies on the alpha-glucosidase inhibitor acarbose in Actinoplanes sp.: source of the maltose unit

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.50.954

Biosynthetic studies of allosamidin. 2. Isolation of didemethylallosamidin, and conversion experiments of 14C-labeled demethylallosamidin, didemethylallosamidin and their related compounds.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1582

Isolation of trehalamine, the aglycon of trehazolin, from microbial broths and characterization of trehazolin related compounds.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1116

Cloning and analysis of a gene (SMS13) encoding sannamycin B-glycyltransferase from Streptomyces sannanensis and its distribution among actinomycetes.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.45.1167

Biosynthesis of astromicin and related antibiotics. II. Biosynthetic studies with blocked mutants of Micromonospora olivasterospora

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.37.1670

Mutational biosynthesis of butirosin analogs. III. 6'-N-methylbutirosins and 3',4'-dideoxy-6'-C-methylbutirosins, new semisynthetic aminoglycosides.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.31.1039

Mutational biosynthesis of butirosin analogs. I. Conversion of neamine analogs into butirosin analogs by mutants of Bacillus circulans.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.31.1023

Studies on the biosynthesis of the alpha-glucosidase inhibitor acarbose: valienamine, a m-C7N unit not derived from the shikimate pathway

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.855

Search for microbial insect growth regulators. II Allosamidin, a novel insect chitinase inhibitor.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.296

Adecypenol, a unique adenosine deaminase inhibitor containing homopurine and cyclopentene rings

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.39.309

Studies on neplanocin A, new antitumor antibiotic. I. Producing organism, isolation and characterization

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.34.359

Streptomyces citricolor nov. sp. and a new antibiotic, aristeromycin

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.21.255

Pactamycin Production by Streptomyces pactum

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/AM.10.4.302-304.1962

Organization and nature of fortimicin A (astromicin) biosynthetic genes studied using a cosmid library of Micromonospora olivasterospora DNA

1 reference

11 May 2024

https://opencitations.net/index/api/v1/citations/10.1007/BF00279641

Identifiers

DOI

10.1039/B603816F

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16 August 2017

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PubMed ID

17390001