(Q36777320)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

review article

1 reference

title

p53 alterations in human cancer: more questions than answers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Soussi T

series ordinal

1

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 April 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

2145-2156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401423%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210280

28 December 2019

exact match

0 references

cites work

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 isoforms can regulate p53 transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53's believe it or not: lessons on transcription-independent death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Cytosine methylation determines hot spots of DNA damage in the human P53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Gain of function mutations in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Functions of the MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 in recombination and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

The P53 pathway: what questions remain to be explored?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

What have animal models taught us about the p53 pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p73: Friend or foe in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

The antioxidant function of the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53: traffic cop at the crossroads of DNA repair and recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Selenomethionine regulation of p53 by a ref1-dependent redox mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Phosphorylation of serine 18 regulates distinct p53 functions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Assessing TP53 status in human tumours to evaluate clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 mutation heterogeneity in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Cancer genes and the pathways they control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Involvement of 5-methylcytosine in sunlight-induced mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Converting p53 from a killer into a healer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promise

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Cellular proofreading

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Different tumor-derived p53 mutants exhibit distinct biological activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p53 modulation of the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Chemosensitivity linked to p73 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p53: oncogene or anti-oncogene?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Flexibility: the key to p53 function?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

p53-dependent apoptosis suppresses radiation-induced teratogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

The continuing saga of p53--more sleepless nights ahead

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021

Evolutionary conservation of the biochemical properties of p53: specific interaction of Xenopus laevis p53 with simian virus 40 large T antigen and mammalian heat shock proteins 70

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210280

7 January 2021