(Q30977773)

27 June 2017

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations (English)

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27 June 2017

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1

Thierry Soussi

1 reference

27 June 2017

Shunsuke Kato

2

1 reference

27 June 2017

Pierre P Levy

series ordinal

3

1 reference

27 June 2017

Chikashi Ishioka

series ordinal

4

1 reference

27 June 2017

1 January 2005

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27 June 2017

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27 June 2017

25

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27 June 2017

6-17

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27 June 2017

1

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

27 June 2017

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Screening for TP53 rearrangements in families with the Li-Fraumeni syndrome reveals a complete deletion of the TP53 gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Rescuing the function of mutant p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Gain of function mutations in p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

A simple p53 functional assay for screening cell lines, blood, and tumors

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Understanding missense mutations in the BRCA1 gene: an evolutionary approach

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

TP53 mutations in human skin cancers.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Screening patients for heterozygous p53 mutations using a functional assay in yeast

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

p53: oncogene or anti-oncogene?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Evaluation of methods to detect p53 mutations in ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Flexibility: the key to p53 function?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Decision making by p53: life, death and cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

p53 compound heterozygosity in a severely affected child with Li-Fraumeni syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Mutations in the TP53 gene in human malignant melanomas derived from sun-exposed skin and unexposed mucosal membranes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Assessing TP53 status in human tumours to evaluate clinical outcome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Molecular basis of inherited diseases: a structural perspective

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

p53, proto-oncogene and rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Germline TP53 mutations and Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Regional analysis of p53 mutations in rheumatoid arthritis synovium

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

No PUMA, no death: implications for p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

A temperature-sensitive mutant of human p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.20114

7 January 2021

Identifiers

DOI

10.1002/HUMU.20114

1 reference

release_sl4mtyhsgrcp7k4dzh67jnncta

27 June 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sl4mtyhsgrcp7k4dzh67jnncta

24 November 2022

mapped directly with Wikidata item

1 reference