(Q36808324)

English

Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251.

scientific article published on 3 February 2009

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20 January 2020

Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251 (English)

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20 January 2020

Simian immunodeficiency virus

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Barbara L Shacklett

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20 January 2020

Francois Villinger

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Francois Villinger

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20 January 2020

Ellen E Sparger

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Ellen E Sparger

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20 January 2020

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Robert A Dubie

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20 January 2020

Saipiroon Maksaereekul

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Donna Lemongello

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Kelly S Cole

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Shelley A Blozis

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Paul A Luciw

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20 January 2020

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20 January 2020

Sequential priming with simian immunodeficiency virus (SIV) DNA vaccines, with or without encoded cytokines, and a replicating adenovirus-SIV recombinant followed by protein boosting does not control a pathogenic SIVmac251 mucosal challenge

1 reference

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Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

1 reference

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29 September 2017

IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

1 reference

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29 September 2017

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

1 reference

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The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements

1 reference

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Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine

1 reference

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Polyfunctional T cell responses are a hallmark of HIV-2 infection

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29 September 2017

Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid

1 reference

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29 September 2017

Adjuvanting a DNA vaccine with a TLR9 ligand plus Flt3 ligand results in enhanced cellular immunity against the simian immunodeficiency virus

1 reference

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29 September 2017

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

1 reference

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29 September 2017

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

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Correlates of immune protection and the development of a human immunodeficiency virus vaccine

1 reference

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29 September 2017

Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.

1 reference

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29 September 2017

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

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Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects

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Progress and obstacles in the development of an AIDS vaccine

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Vaccination of cats with attenuated feline immunodeficiency virus proviral DNA vaccine expressing gamma interferon

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Cytokine-adjuvanted HIV-DNA vaccination strategies

1 reference

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29 September 2017

DNA vaccines for HIV: challenges and opportunities.

1 reference

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29 September 2017

Coimmunization with IL-15 plasmid enhances the longevity of CD8 T cells induced by DNA encoding hepatitis B virus core antigen

1 reference

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29 September 2017

Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection

1 reference

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29 September 2017

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

1 reference

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29 September 2017

Homeostasis of memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640844

29 September 2017

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

1 reference

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29 September 2017

Gene-based vaccines: recent technical and clinical advances

1 reference

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29 September 2017

Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

1 reference

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29 September 2017

A period of transient viremia and occult infection precedes persistent viremia and antiviral immune responses during multiple low-dose intravaginal simian immunodeficiency virus inoculations

1 reference

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29 September 2017

IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques

1 reference

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29 September 2017

Approaches for the design and evaluation of HIV-1 DNA vaccines

1 reference

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29 September 2017

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

1 reference

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29 September 2017

Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.

1 reference

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29 September 2017

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

1 reference

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Regulation of naïve and memory T-cell homeostasis

1 reference

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Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

1 reference

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Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

1 reference

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Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

1 reference

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29 September 2017

Occult systemic infection and persistent simian immunodeficiency virus (SIV)-specific CD4(+)-T-cell proliferative responses in rhesus macaques that were transiently viremic after intravaginal inoculation of SIV

1 reference

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Identification of highly attenuated mutants of simian immunodeficiency virus

1 reference

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Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity

1 reference

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Requirement of caprine arthritis encephalitis virus vif gene for in vivo replication

1 reference

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29 September 2017

The requirement for Vif of SIVmac is cell-type dependent

1 reference

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29 September 2017

Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys.

1 reference

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29 September 2017

IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses

1 reference

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27 June 2018

Interleukin-15 increases effector memory CD8+ t cells and NK Cells in simian immunodeficiency virus-infected macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640844

27 June 2018

Protective immunity against feline immunodeficiency virus induced by inoculation with vif-deleted proviral DNA.

1 reference

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27 June 2018

A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals

1 reference

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Sustained suppression of SHIV89.6P replication in macaques by vaccine-induced CD8+ memory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640844

5 September 2018

Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3640844

5 September 2018

Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques

1 reference

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5 September 2018

Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques.

1 reference

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5 September 2018

Prolonged exposure of naïve CD8+ T cells to interleukin-7 or interleukin-15 stimulates proliferation without differentiation or loss of telomere length.

1 reference

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5 September 2018

Differential effect of IL-15 and IL-2 on survival of phytohemagglutinin-activated umbilical cord blood T cells.

1 reference

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5 September 2018

Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

1 reference

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5 September 2018

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1 reference

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5 September 2018

Real-time TaqMan PCR as a specific and more sensitive alternative to the branched-chain DNA assay for quantitation of simian immunodeficiency virus RNA.

1 reference

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Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection

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5 September 2018

Comparative sequence analysis of cytokine genes from human and nonhuman primates.

1 reference

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5 September 2018

Safety and Immunogenicity of a Replication‐Incompetent Adenovirus Type 5 HIV‐1 Clade Bgag/pol/nefVaccine in Healthy Adults

1 reference

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4 December 2018

Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.01.007

7 January 2021

Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2009.01.007

7 January 2021

AIDS vaccine models: challenging challenge viruses

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7 January 2021

Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids

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7 January 2021

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

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7 January 2021

Identifiers

10.1016/J.VIROL.2009.01.007

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20 January 2020

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Europe PubMed Central

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20 January 2020

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20 January 2020

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