(Q36822322)

16 August 2017

1 reference

title

Huntington's disease: pathological mechanisms and therapeutic strategies (English)

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16 August 2017

0 references

3

Jeffrey H Kordower

1 reference

16 August 2017

Shilpa Ramaswamy

1

1 reference

16 August 2017

Kathleen M Shannon

series ordinal

2

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16 August 2017

publication date

1 January 2007

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16 August 2017

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16 August 2017

volume

16

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16 August 2017

issue

3

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16 August 2017

page(s)

301-312

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The functional anatomy of basal ganglia disorders

16 August 2017

cites work

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21 January 2018

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21 January 2018

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21 January 2018

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Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study

21 January 2018

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Safety and tolerability assessment of intrastriatal neural allografts in five patients with Huntington's disease

21 January 2018

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Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF.

21 January 2018

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Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study

21 January 2018

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Motor and cognitive improvements in patients with Huntington's disease after neural transplantation

21 January 2018

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Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study.

21 January 2018

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Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat.

21 January 2018

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A review of the treatment options for Huntington's disease

21 January 2018

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Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

21 January 2018

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Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

21 January 2018

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Aspects of procedural memory are differentially impaired in Huntington's disease.

21 January 2018

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Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease

21 January 2018

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Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

21 January 2018

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Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference.

21 January 2018

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Predictive, pre-natal and diagnostic genetic testing for Huntington's disease: the experience in Canada from 1987 to 2000.

21 January 2018

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RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys

21 January 2018

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Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice

21 January 2018

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GDNF family ligands display distinct action profiles on cultured GABAergic and serotonergic neurons of rat ventral mesencephalon

21 January 2018

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Striatal transplantation in a transgenic mouse model of Huntington's disease

21 January 2018

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Cell therapy in Huntington's disease.

21 January 2018

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Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization

21 January 2018

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Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology

21 January 2018

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Huntington's disease: pathomechanism and therapeutic perspectives

21 January 2018

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Striatal neural grafting improves cortical metabolism in Huntington's disease patients

21 January 2018

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

21 January 2018

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Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members

21 January 2018

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Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

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Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid

21 January 2018

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Are cognitive changes the first symptoms of Huntington's disease? A study of gene carriers

21 January 2018

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Genetic testing for Huntington's disease

21 January 2018

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RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

21 January 2018

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Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

21 January 2018

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The use of transgenic and knock-in mice to study Huntington's disease.

21 January 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial

21 January 2018

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On chorea. George Huntington, M.D.

21 January 2018

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Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting.

21 January 2018

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Graft-induced behavioral recovery in an animal model of Huntington disease

21 January 2018

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Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Genetic testing in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Safety of intrastriatal neurotransplantation for Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Comparison of executive and visuospatial memory function in Huntington's disease and dementia of Alzheimer type matched for degree of dementia

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model

21 January 2018

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Autologous adult bone marrow stem cell transplantation in an animal model of huntington's disease: behavioral and morphological outcomes

21 January 2018

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IV amantadine improves chorea in Huntington's disease: an acute randomized, controlled study

21 January 2018

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rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse

21 January 2018

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https://api.crossref.org/works/10.3727%2F000000007783464687

Human neural stem cell transplants improve motor function in a rat model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Knock-in mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Ontogeny of human striatal DARPP-32 neurons in fetuses and following xenografting to the adult rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

siRNA-mediated inhibition of endogenous Huntington disease gene expression induces an aberrant configuration of the ER network in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Tetrabenazine treatment for Huntington's disease-associated chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

A randomized trial of amantadine in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Incidence and mutation rates of Huntington's disease in Spain: experience of 9 years of direct genetic testing

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Differential loss of striatal projection neurons in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Intrastriatal injections of quinolinic acid or kainic acid: differential patterns of cell survival and the effects of data analysis on outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Transgenic models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Huntington's disease confirmed by genetic testing in five African families

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Creatine therapy for Huntington's disease: clinical and MRS findings in a 1-year pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

A randomised, placebo-controlled, double blind study of treatment of Huntington's disease with unsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Clozapine versus placebo in Huntington's disease: a double blind randomised comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Transgenic rat model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000007783464687

10.3727/000000007783464687

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference