(Q36844711)

16 August 2017

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title

The contribution of immunology to the rational design of novel antibacterial vaccines (English)

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16 August 2017

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Stefan H E Kaufmann

1

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language of work or name

English

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publication date

1 July 2007

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Nature Reviews Microbiology

16 August 2017

published in

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16 August 2017

volume

5

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16 August 2017

issue

7

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16 August 2017

page(s)

491-504

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https://scigraph.springernature.com/pub.10.1038/nrmicro1688

16 August 2017

exact match

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cites work

Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity.

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Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guérin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara

21 January 2018

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Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

21 January 2018

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Inducible costimulator protein controls the protective T cell response against Listeria monocytogenes

21 January 2018

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Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

Staphylococcus aureus infections

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

The antibiotic resistome: the nexus of chemical and genetic diversity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

Re-emergence of early pandemic Staphylococcus aureus as a community-acquired meticillin-resistant clone.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

Antibacterial resistance worldwide: causes, challenges and responses

31 March 2020

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Problem pulmonary pathogens: Pseudomonas aeruinosa

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

Medicine. The intangible value of vaccination

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

Maintenance of serum antibody levels

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

A reappraisal of humoral immunity based on mechanisms of antibody-mediated protection against intracellular pathogens

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1688

A synthetic conjugate polysaccharide vaccine against Haemophilus influenzae type b

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Pneumococcal vaccines: do they prevent infection and how?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

A review of vaccine research and development: meningococcal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Cell-mediated immunity and the challenges for vaccine development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

T cell memory and protective immunity by vaccination: is more better?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Translating innate immunity into immunological memory: implications for vaccine development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Immunological memory and protective immunity: understanding their relation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Differentiation of memory B and T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Regulation of immune responses by T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Natural regulatory T cells in infectious disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

T-cell homing specificity and plasticity: new concepts and future challenges

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Mucosal vaccines: the promise and the challenge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Pathogen recognition and innate immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Intracellular pattern recognition receptors in the host response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Dendritic cells at the host-pathogen interface

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

No life without death--apoptosis as prerequisite for T cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

All in the family: IL-27 suppression of T(H)-17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Helper T cell differentiation enters a new era: le roi est mort; vive le roi!

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Th17: an effector CD4 T cell lineage with regulatory T cell ties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Reshaping the past: Strategies for modulating T-cell memory immune responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

31 March 2020

The B7 family revisited

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Dendritic cells transfected with cytopathic self-replicating RNA induce crosspriming of CD8+ T cells and antiviral immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Manipulation and potentiation of antimycobacterial immunity using recombinant bacille Calmette-Guérin strains that secrete cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Directed antigen delivery as a vaccine strategy for an intracellular bacterial pathogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Control of antigen presentation by a single protease cleavage site

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Th1 memory: implications for vaccine development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Central memory and effector memory T cell subsets: function, generation, and maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The descent of memory T-cell subsets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Class II-independent generation of CD4 memory T cells from effectors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Differential contributions of central and effector memory T cells to recall responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The many roles of chemokines and chemokine receptors in inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Application of mycobacterial proteomics to vaccine design: improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Control of T cell viability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

T-cell co-stimulation through B7RP-1 and ICOS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

B-cell memory: are subsets necessary?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Understanding and making use of human memory B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Memory B-cell persistence is independent of persisting immunizing antigen.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Lifetime of plasma cells in the bone marrow.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Humoral immunity due to long-lived plasma cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Control of B-cell responses by Toll-like receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Maintenance of serological memory by polyclonal activation of human memory B cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Group B Streptococcus: global incidence and vaccine development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Staphylococcal vaccines and immunotherapy: to dream the impossible dream?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Staphylococci in colonization and disease: prospective targets for drugs and vaccines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Safety and immunogenicity of a recombinant multivalent group a streptococcal vaccine in healthy adults: phase 1 trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Identification of a universal Group B streptococcus vaccine by multiple genome screen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Microbial genomes and vaccine design: refinements to the classical reverse vaccinology approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Immunomics: discovering new targets for vaccines and therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Recent findings in immunology give tuberculosis vaccines a new boost

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Envisioning future strategies for vaccination against tuberculosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The Development and Impact of Tuberculosis Vaccines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

The success and failure of BCG - implications for a novel tuberculosis vaccine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Helicobacter pylori vaccine development: facing the challenge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Helicobacter pyloriInfection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Anti-infective antibodies: finding the path forward

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Immunology. Considering therapeutic antibodies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Defensin: a multifunctional molecule lives up to its versatile name.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Cost-effectiveness of pneumococcal conjugate vaccination in the prevention of child mortality: an international economic analysis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Invasive group A streptococcal disease: should close contacts routinely receive antibiotic prophylaxis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Molecular basis of group A streptococcal virulence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

Host-pathogen interactions in Streptococcus pyogenes infections, with special reference to puerperal fever and a comment on vaccine development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1688

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1688

1 reference

16 August 2017

1 reference