(Q36853695)

16 August 2017

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title

Cellular senescence and chromatin structure (English)

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16 August 2017

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Ryo Funayama

1

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16 August 2017

Fuyuki Ishikawa

series ordinal

2

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16 August 2017

publication date

20 June 2007

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16 August 2017

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16 August 2017

volume

116

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16 August 2017

issue

5

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16 August 2017

page(s)

431-440

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

16 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00412-007-0115-7

Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00412-007-0115-7

HMGI/Y proteins: flexible regulators of transcription and chromatin structure

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00412-007-0115-7

Human LATS1 is a mitotic exit network kinase

21 January 2018

1 reference

12 December 2020

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

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12 December 2020

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

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12 December 2020

The regulation of E2F by pRB-family proteins

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12 December 2020

Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells

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12 December 2020

Nuclear RNAs confined to a reticular compartment between chromosome territories

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12 December 2020

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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12 December 2020

Telomeres shorten during ageing of human fibroblasts

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12 December 2020

Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

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12 December 2020

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

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12 December 2020

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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12 December 2020

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

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12 December 2020

Senescence, apoptosis and therapy--cutting the lifelines of cancer.

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12 December 2020

Chromosome territories--a functional nuclear landscape.

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12 December 2020

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

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12 December 2020

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

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12 December 2020

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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12 December 2020

HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family

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12 December 2020

A role for both RB and p53 in the regulation of human cellular senescence

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12 December 2020

Nucleosomes and the chromatin fiber

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12 December 2020

Cell enlargement: one possible mechanism underlying cellular senescence

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12 December 2020

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

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12 December 2020

Transcriptional activation triggers deposition and removal of the histone variant H3.3.

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12 December 2020

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

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12 December 2020

Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

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12 December 2020

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

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12 December 2020

Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts

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12 December 2020

LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1

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12 December 2020

DNA damage checkpoint kinase Chk2 triggers replicative senescence

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12 December 2020

The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly

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12 December 2020

The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives

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12 December 2020

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

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12 December 2020

Developmental changes in histone macroH2A1-mediated gene regulation

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12 December 2020

Historical claims and current interpretations of replicative aging

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12 December 2020

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

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12 December 2020

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

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12 December 2020

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

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12 December 2020

Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes

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12 December 2020

Identification of an interchromosomal compartment by polymerization of nuclear-targeted vimentin

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12 December 2020

Tumour biology: senescence in premalignant tumours

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12 December 2020

HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells.

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12 December 2020

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

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12 December 2020

The signals and pathways activating cellular senescence

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12 December 2020

Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism

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12 December 2020

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures

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12 December 2020

Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin

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12 December 2020

Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

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12 December 2020

Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI-38 cells by simian virus 40 infection

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12 December 2020

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

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12 December 2020

A DNA damage checkpoint response in telomere-initiated senescence

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12 December 2020

Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function

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12 December 2020

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts

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12 December 2020

Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery

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12 December 2020

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

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12 December 2020

Oncogene-induced senescence as an initial barrier in lymphoma development

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12 December 2020

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12 December 2020

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

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12 December 2020

Loss of linker histone H1 in cellular senescence

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12 December 2020

Induction of senescence in human malignant glioma cells by p16INK4A.

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12 December 2020

The serial cultivation of human diploid cell strains

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12 December 2020

Different telomere damage signaling pathways in human and mouse cells

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12 December 2020

Developmental differences in the immortalization of lung fibroblasts by telomerase

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12 December 2020

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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12 December 2020

PRAK is essential for ras-induced senescence and tumor suppression

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12 December 2020

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

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12 December 2020

Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing

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12 December 2020

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

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12 December 2020

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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12 December 2020

The HBP1 transcriptional repressor participates in RAS-induced premature senescence

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12 December 2020

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin

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12 December 2020

The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway

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12 December 2020

Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

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12 December 2020

Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation

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12 December 2020

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

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12 December 2020

HMG chromosomal proteins in development and disease

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12 December 2020

Extension of life-span by introduction of telomerase into normal human cells

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12 December 2020

Cancer and aging: a model for the cancer promoting effects of the aging stroma

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12 December 2020

Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes

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12 December 2020

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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12 December 2020

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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12 December 2020

Molecular dissection of formation of senescence-associated heterochromatin foci

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12 December 2020

Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction

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12 December 2020

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

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12 December 2020

PRAK, a novel protein kinase regulated by the p38 MAP kinase

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12 December 2020

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice

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12 December 2020

Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries

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12 December 2020

Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

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12 December 2020

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis

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12 December 2020

The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathways

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12 December 2020

Reversal of human cellular senescence: roles of the p53 and p16 pathways

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12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

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12 December 2020

Molecular biology of HMGA proteins: hubs of nuclear function

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12 December 2020

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

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12 December 2020

BRAFE600-associated senescence-like cell cycle arrest of human naevi

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12 December 2020

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

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12 December 2020

10.1007/S00412-007-0115-7

Identifiers

DOI

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16 August 2017

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