(Q36871056)

16 August 2017

1 reference

title

Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs (English)

1 reference

16 August 2017

Yasuhiro Masubuchi

1

1 reference

16 August 2017

Toshiharu Horie

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

1 June 2007

1 reference

Critical Reviews in Toxicology

16 August 2017

published in

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16 August 2017

volume

37

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16 August 2017

issue

5

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16 August 2017

page(s)

389-412

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Induction of heme oxygenase in toxic renal injury: a protective role in cisplatin nephrotoxicity in the rat.

16 August 2017

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Free radical mechanisms in immune reactions associated with alcoholic liver disease.

21 January 2018

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Cardiovascular drug-drug interactions

21 January 2018

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Demonstration of halothane-induced hepatic lipid peroxidation in rats by quantification of F2-isoprostanes.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440701215233

Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440701215233

Immunotoxicology of the liver: adverse reactions to drugs

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440701215233

Cisapride. Drug interactions of clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Determination of the structure of an N-substituted protoporphyrin isolated from the livers of griseofulvin-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450IA2. A specific marker of dihydralazine-induced hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Aromatase inhibitors in the treatment of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Relevance of cytochrome P450 levels in the actions of enflurane and isoflurane in mice: studies on the haem pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Determinants of protein modification versus heme alkylation: inactivation of cytochrome P450 1A1 by 1-ethynylpyrene and phenylacetylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Degradation of rat liver cytochromes P450 3A after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: characterization of the proteolytic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential apoprotein loss of rat liver cytochromes P450 after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: a case for distinct proteolytic mechanisms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Liver production of N-alkylated porphyrins caused in mice by treatment with substituted dihydropyridines. Evidence that the alkyl group on the pyrrole nitrogen atom originates from the drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Occurrence and biological properties of N-methyl protoporphyrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inhibition of protohaem ferro-lyase by N-substituted porphyrins. Structural requirements for the inhibitory effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inactivation of cytochrome P-450 and production of N-alkylated porphyrins caused in isolated hepatocytes by substituted dihydropyridines. Structural requirements for loss of haem and alkylation of the pyrrole nitrogen atom

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Alteration of hepatic microsomal enzymes by griseofulvin treatment of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Examination of purported probes of human CYP2B6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Expression of autoantibodies to specific cytochromes P450 in a case of disulfiram hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Comparison of the formation of N-alkylprotoporphyrin IX after interaction of porphyrinogenic xenobiotics with single cDNA-expressed human P450 enzymes in microsomes prepared from baculovirus-infected insect cells and human lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Uroporphyria in mice: thresholds for hepatic CYP1A2 and iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Drug metabolism, danger signals, and drug-induced hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Structural basis of selective cytochrome P450 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Selective inhibitors of cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Therapeutic advantages of third generation antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Identification of the heme adduct and an active site peptide modified during mechanism-based inactivation of rat liver cytochrome P450 2B1 by secobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Antiprogestin-mediated inactivation of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Idiosyncratic drug hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivators as probes of cytochrome P450 structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential oxidation of mifepristone by cytochromes P450 3A4 and 3A5: selective inactivation of P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Midazolam oxidation by cytochrome P450 3A4 and active-site mutants: an evaluation of multiple binding sites and of the metabolic pathway that leads to enzyme inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Identification of the enzyme responsible for oxidative halothane metabolism: implications for prevention of halothane hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of P450 2A6 by furanocoumarins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Drug-drug interactions of new active substances: mibefradil example

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochrome P-450 and halothane metabolism. Decrease in rat liver microsomal P-450 in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Free heme toxicity and its detoxification systems in human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Identification of human hepatic cytochrome P450 sources of N-alkylprotoporphyrin IX after interaction with porphyrinogenic xenobiotics, implications for detection of xenobiotic-induced porphyria in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The mechanism of the suicidal reductive inactivation of microsomal cytochrome P-450 by halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Suicidal inactivation of human cytochrome P-450 by carbon tetrachloride and halothane in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochromes P450 and uridine triphosphate-glucuronosyltransferases: model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Selective inactivation of rat and bovine olfactory cytochrome P450 by three haloethanes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Fatal hepatitis associated with isoflurane exposure and CYP2A6 autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Diclofenac-induced inactivation of CYP3A4 and its stimulation by quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Tolerance, danger, and the extended family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Drug interactions with cisapride: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Life-threatening interaction of mibefradil and beta-blockers with dihydropyridine calcium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanisms of the inhibition of cytochrome P-450-mediated drug oxidation by therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Drug-mediated inactivation of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Protective role of heme oxygenase-1 induction in carbon tetrachloride-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cytochromes P450 and UDP-glucuronosyl-transferases as hepatocellular autoantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Prevention of halothane-induced hepatotoxicity by hemin pretreatment: protective role of heme oxygenase-1 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Suicidal destruction of cytochrome P-450 during oxidative drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cardiotoxicity of new antihistamines and cisapride

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Torsades de pointes induced by erythromycin and terfenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The importance of drug interactions in epilepsy therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Pharmacokinetic drug interactions of macrolides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The danger hypothesis--potential role in idiosyncratic drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Neoantigens associated with halothane hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The immunologic and metabolic basis of drug hypersensitivities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of human cytochrome P4502C8 by drugs in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inactivation of human cytochrome P450 1A2 by furafylline: detection of a 1:1 adduct to protein and evidence for the formation of a novel imidazomethide intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Regulation of CYP 2 A 5 induction by porphyrinogenic agents in mouse primary hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Management of oxidative stress by heme oxygenase-1 in cisplatin-induced toxicity in renal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Platinum neurotoxicity: clinical profiles, experimental models and neuroprotective approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

The danger hypothesis applied to idiosyncratic drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Interactions between drugs for erectile dysfunction and drugs for cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Clinically significant pharmacokinetic drug interactions with carbamazepine. An update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Effect of tamoxifen on the enzymatic activity of human cytochrome CYP2B6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Porphyrinogenic activity and ferrochelatase-inhibitory activity of sydnones in chick embryo liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Clinically significant pharmacokinetic drug interactions with benzodiazepines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inhibition selectivity of grapefruit juice components on human cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inactivation of human liver cytochrome P-450 by the drug methoxsalen and other psoralen derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

New concepts in immunology relevant to idiosyncratic drug reactions: the "danger hypothesis" and innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Pharmacokinetic interactions between theophylline and other medication (Part I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Macrolide antibacterials. Drug interactions of clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Different faces of the heme-heme oxygenase system in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Clinical pharmacokinetics of mibefradil

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Cardiac actions of antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Differential effects of isoflurane and halothane on the induction of heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Fluvoxamine-theophylline interaction: gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Reversible and irreversible inhibition of CYP3A enzymes by tamoxifen and metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Inhibition of Cytochrome P450 Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Oxidation of Tienilic Acid by Human Yeast-Expressed Cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this Drug is A Mechanism-Based Inhibitor Specific for Cytochrome P-450 2C9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

Identification of N-methylprotoporphyrin IX in livers of untreated mice and mice treated with 3,5-diethoxycarbonyl-1,4-dihydrocollidine: Source of the methyl group

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440701215233

10.1080/10408440701215233

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference