(Q36871625)

16 August 2017

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title

Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis (English)

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16 August 2017

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1

Susan J Clark

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16 August 2017

1 April 2007

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16 August 2017

Human Molecular Genetics

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16 August 2017

16 Spec No 1

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16 August 2017

R88-95

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Epigenetics in Carcinogenesis and Cancer Prevention

16 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The history of cancer epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The epigenetics of cancer etiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The epigenetic progenitor origin of human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The cancer epigenome--components and functional correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

CpG islands in vertebrate genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The Sequence of the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Number of CpG islands and genes in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation patterns and epigenetic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

X inactivation, differentiation, and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Changes in DNA methylation during mouse embryonic development in relation to X-chromosome activity and imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic reprogramming in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Dynamic reprogramming of DNA methylation in the early mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic reprogramming in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Targeting cellular memory to reprogram the epigenome, restore potential, and improve somatic cell nuclear transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

High sensitivity mapping of methylated cytosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation profile of the mouse skeletal alpha-actin promoter during development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

CpG methylation is maintained in human cancer cells lacking DNMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation and imprinting: why bother?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Lsh, a member of the SNF2 family, is required for genome-wide methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Lsh is involved in de novo methylation of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Gene silencing in mammalian cells and the spread of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Predicting aberrant CpG island methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA motifs associated with aberrant CpG island methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Methylation changes in the apolipoprotein AI gene during embryonic development of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

RNA-directed DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

RNA-based silencing strategies in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Cellular memory and the histone code

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Role of histone H3 lysine 27 methylation in X inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Polycomb complexes and silencing mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Molecular biology. "X"-rated chromosomal rendezvous.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Cross-species clues of an epigenetic imprinting regulatory code for the IGF2R gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Identification of transcribed sequences in Arabidopsis thaliana by using high-resolution genome tiling arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Oncomirs - microRNAs with a role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Clustering of hypermethylated genes in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic inactivation of the HOXA gene cluster in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Regional copy number-independent deregulation of transcription in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

X-chromosome inactivation: closing in on proteins that bind Xist RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

X chromosome imprinting and inactivation in preimplantation mammalian embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Xist RNA and the mechanism of X chromosome inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Small interfering RNA-induced transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Altered DNA methylation and genome instability: a new pathway to cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Suppression of intestinal neoplasia by deletion of Dnmt3b

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation and gene silencing in cancer: which is the guilty party?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Altered methylation patterns in cancer cell genomes: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Polycomb silencers control cell fate, development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Epigenetic stem cell signature in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Implication of abnormal epigenetic patterns for human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Evidence for an instructive mechanism of de novo methylation in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

RNA interference is required for normal centromere function in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Global effects on gene expression in fission yeast by silencing and RNA interference machineries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

DNA methylation profiling of human chromosomes 6, 20 and 22

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

Demethylation of the zygotic paternal genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM051

21 January 2018

Identifiers

DOI

10.1093/HMG/DDM051

1 reference

16 August 2017

1 reference

PubMed ID

17613553