(Q36884785)

16 August 2017

Evidence That Does Not Support Pyruvate Kinase M2 (PKM2)-catalyzed Reaction as a Rate-limiting Step in Cancer Cell Glycolysis (English)

1 reference

16 August 2017

Jiansheng Xie

1

1 reference

16 August 2017

Chunyan Dai

series ordinal

2

1 reference

16 August 2017

Xun Hu

series ordinal

3

1 reference

16 August 2017

language of work or name

English

0 references

publication date

25 February 2016

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

291

1 reference

16 August 2017

17

1 reference

16 August 2017

8987-8999

1 reference

Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Beyond Warburg effect--dual metabolic nature of cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

A database of thermodynamic properties of the reactions of glycolysis, the tricarboxylic acid cycle, and the pentose phosphate pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Regulation of cancer cell metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Pyruvate kinase M2 is a phosphotyrosine-binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Allosteric regulation of pyruvate kinase M2 isozyme involves a cysteine residue in the intersubunit contact

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Enzymes of glucose metabolism in carcinoma of the cervix and endometrium of the human uterus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Application of a microchemical technique to the elucidation of enzyme activity profiles within single human mammary tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

The glycolytic enzyme activity of the human cervix uteri

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Control of phosphofructokinase from rat skeletal muscle. Effects of fructose diphosphate, AMP, ATP, and citrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Glycolytic enzymes from human neuroectodermal tumors of childhood

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Brain hexokinase. A proposed relation between soluble-particulate distribution and activity in vivo.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

pH-dependence of the triose phosphate isomerase reaction

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

The isolation and specific activity of rabbit-muscle glyceraldehyde phosphate dehydrogenase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Enolase exists in the fluid phase of cytoplasm in 3T3 cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Regulation of M2-type pyruvate kinase from human meningioma by allosteric effectors fructose 1,6 diphosphate and L-alanine.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Biochemical thermodynamics under near physiological conditions.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Biochemical thermodynamics: applications of Mathematica.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Characterization of some glycolytic enzymes from human retina and retinoblastoma.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Crystalline 3-phosphoglycerate kinase from skeletal muscle

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Allosteric character of the inhibition of rat-muscle hexokinase B by glucose 6-phosphate.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861469

Control analysis of metabolic systems

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.704825

Enzyme activities in normal, dysplastic, and cancerous human breast tissues

21 January 2018

1 reference

12 December 2020

Synergistic effect of ammonium and potassium ions on pyruvate kinase from Ehrlich ascites tumor cells

1 reference

12 December 2020

Glycolytic enzyme activities in breast cancer metastases

1 reference

12 December 2020

Purification and some properties of phosphorylglyceric acid mutase from rabbit skeletal muscle

1 reference

12 December 2020

Subunit structure and chemical properties of rabbit liver aldolase

1 reference

12 December 2020

Isozyme distribution of hexokinase, phosphofructokinase and pyruvate kinase in lymphocytes from patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Control of glycolysis in rat liver by glucokinase and phosphofructokinase: influence of glucose concentration

1 reference

12 December 2020

Studies of the phosphoglucose isomerase of Schistosoma mansoni

1 reference

12 December 2020

Pyruvate kinase type M2: a key regulator within the tumour metabolome and a tool for metabolic profiling of tumours

1 reference

12 December 2020

Enzyme activities and isozyme patterns in human lung tumors

1 reference

12 December 2020

Studies on certain cytoplasmic enzymes and specific estrogen receptors in human breast cancer and in nonmalignant diseases of the breast

1 reference

12 December 2020

Enzymes, nucleic acids, and lipids in human breast cancer and normal breast tissue

1 reference

12 December 2020

Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue

1 reference

12 December 2020

Activities and isoenzyme patterns of some enzymes of glucose metabolism in human primary malignant hepatoma

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M115.704825

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

26917721

1 reference