(Q36936674)

17 August 2017

1 reference

title

Drug metabolism in carcinogenesis and cancer chemotherapy (English)

1 reference

17 August 2017

1 reference

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

22 November 2022

author name string

M. A. Graham

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1784632

22 November 2022

R. J. Riley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1784632

22 November 2022

D. J. Kerr

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1784632

22 November 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1784632

22 November 2022

publication date

1 January 1991

1 reference

full work available at URL

17 August 2017

https://api.elsevier.com/content/article/PII:016372589190083X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

https://api.elsevier.com/content/article/PII:016372589190083X?httpAccept=text/plain

22 November 2022

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Pharmacology & Therapeutics

22 November 2022

published in

1 reference

17 August 2017

51

1 reference

17 August 2017

275-289

1 reference

17 August 2017

2

1 reference

The effect of cimetidine on cyclophosphamide metabolism in rabbits

17 August 2017

2

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

22 November 2022

3

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Isolation and characterization of 4-ipomeanol, a lung-toxic furanoterpenoid produced by sweet potatoes (Ipomoea batatas)

22 November 2022

6

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas) following microbial infection

22 November 2022

7

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.

22 November 2022

8

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer

22 November 2022

9

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The role of glutathione and glutathione transferases in chemical carcinogenesis

22 November 2022

11

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

22 November 2022

13

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Transfection of a human cytochrome P-450 gene into the human lymphoblastoid cell line, AHH-1, and use of the recombinant cell line in gene mutation assays

22 November 2022

14

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Mitoxantrone affects topoisomerase activities in human breast cancer cells

22 November 2022

15

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Effect of phenytoin on the pharmacokinetics of doxorubicin and doxorubicinol in the rabbit

22 November 2022

16

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Pulmonary metabolism of mutagens and its relationship with lung cancer and smoking habits

22 November 2022

17

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Effect of anthracycline antibiotics on oxygen radical formation in rat heart

22 November 2022

19

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Interaction of cimetidine but not ranitidine with cyclophosphamide in mice

22 November 2022

20

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells

22 November 2022

22

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Oxidative destruction of DNA by the adriamycin-iron complex.

22 November 2022

24

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemia

22 November 2022

25

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

DNA adducts formed from the probable proximate carcinogen, N-hydroxy-3,2' -dimethyl-4-aminobiphenyl, by acid catalysis or S-acetyl coenzyme A-dependent enzymatic esterification.

22 November 2022

26

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen N-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine N-acetyltransferase phenotype

22 November 2022

27

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Pharmacology and Clinical Toxicity of 4'-Iodo-4'-deoxydoxorubicin: An Example of Successful Application of Pharmacokinetics to Dose Escalation in Phase I Trials

22 November 2022

28

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases

22 November 2022

29

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The effect of the anthrapyrazole antitumour agent CI941 on rat liver microsome and cytochrome P-450 reductase mediated free radical processes. Inhibition of doxorubicin activation in vitro

22 November 2022

30

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Biochemical and molecular epidemiology of human cancer: indicators of carcinogen exposure, DNA damage, and genetic predisposition

22 November 2022

33

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Genetic polymorphism and cancer susceptibility: evidence concerning acetyltransferases and cancer of the urinary bladder

22 November 2022

34

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The genetic defect of mephenytoin hydroxylation

22 November 2022

37

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling

22 November 2022

38

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation

22 November 2022

39

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma.

22 November 2022

40

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The effect of verapamil on the pharmacokinetics of adriamycin.

22 November 2022

41

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Acetylator genotype-dependent expression of arylamine N-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients

22 November 2022

42

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Association of DNA cross-linking with potentiation of the morpholino derivative of doxorubicin by human liver microsomes

22 November 2022

45

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

22 November 2022

50

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines

22 November 2022

51

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

P450 genes: structure, evolution, and regulation

22 November 2022

54

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The effect of cimetidine, phenobarbitone and buthionine sulphoximine on the disposition of N-5-dimethyl-9-[(2-methoxy-4-methyl-sulphonylamino)phenylamino]- 4-acridinecarboxamide (CI-921) in the rabbit

22 November 2022

55

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Autocatalytic quinone methide formation from mitomycin c.

22 November 2022

56

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Reactive metabolites from the bioactivation of toxic methylfurans

22 November 2022

59

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Interaction of the peroxidase-derived metabolite of mitoxantrone with nucleic acids. Evidence for covalent binding of 14C-labeled drug

22 November 2022

61

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Enzymology of the reduction of the potent benzotriazine-di-n-oxide hypoxic cell cytotoxin SR 4233 (win 59075) by NAD(P)H: (Quinone acceptor) oxidoreductase (EC 1.6.99.2) purified from walker 256 rat tumour cells

22 November 2022

62

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial

22 November 2022

63

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer

22 November 2022

65

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study

22 November 2022

66

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells

22 November 2022

67

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Adriamycin-stimulated hydroxyl radical formation in human breast tumor cells

22 November 2022

68

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Preclinical toxicology studies of 4-ipomeanol: a novel candidate for clinical evaluation in lung cancer

22 November 2022

70

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Quantitation of specific serum glycoproteins in malignancy

22 November 2022

71

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Antipyrine metabolism in patients with disseminated testicular cancer and the influence of cytostatic treatment

22 November 2022

72

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides

22 November 2022

73

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

The action of oncogenes in the cytoplasm and nucleus.

22 November 2022

74

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Current concepts and controversies in chemical carcinogenesis

22 November 2022

75

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Growth factors, oncogenes, and multistage carcinogenesis

22 November 2022

76

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Anthracycline analogs: the past, present, and future

22 November 2022

77

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

Bioactivation of N-arylhydroxamic acids by rat hepatic N-acetyltransferase. Detection of multiple enzyme forms by mechanism-based inactivation.

22 November 2022

78

1 reference

https://api.crossref.org/works/10.1016/0163-7258(91)90083-X

22 November 2022

Identifiers

1 reference

17 August 2017

1 reference