(Q36967306)

17 August 2017

1 reference

title

Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application (English)

1 reference

17 August 2017

1 reference

4

Ralph R Weichselbaum

1 reference

17 August 2017

Kerrington D Smith

1

1 reference

17 August 2017

Michael Y Shao

series ordinal

2

1 reference

17 August 2017

Mitchell C Posner

series ordinal

3

1 reference

17 August 2017

language of work or name

English

0 references

publication date

1 October 2007

1 reference

17 August 2017

1 reference

17 August 2017

volume

3

1 reference

17 August 2017

issue

5

1 reference

17 August 2017

page(s)

545-556

1 reference

The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Interferon inhibits viral protein synthesis in L cells infected with vaccinia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of her

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Val193 and Phe195 of the gamma 1 34.5 protein of herpes simplex virus 1 are required for viral resistance to interferon-alpha/beta

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Targets and mechanisms for the regulation of translation in malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Creation of human tumour cells with defined genetic elements

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Rsk1 mediates a MEK-MAP kinase cell survival signal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Targeting the mitogen-activated protein kinase cascade to treat cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Viral oncolysis by herpes simplex virus and other viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Enhanced antiglioma activity of chimeric HCMV/HSV-1 oncolytic viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Positron emission tomography of herpes simplex virus 1 oncolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Humoral response to herpes simplex virus is complement-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

The complement response against an oncolytic virus is species-specific in its activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Quantitation of HSV mass distribution in a rodent brain tumor model.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.3.5.545

21 January 2018

Identifiers

DOI

10.2217/14796694.3.5.545

1 reference

release_mua65z4cfncrnb2gj26bwc2vey

17 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mua65z4cfncrnb2gj26bwc2vey

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference