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In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas
scholarly article
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scholarly article
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Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Kylie D. Mason
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Suzanne Cory
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
David C Huang
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Andrew W. Roberts
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Andrew Wei
object named as
Andrew H Wei
series ordinal
4
0 references
Clare L Scott
object named as
Clare L Scott
series ordinal
3
0 references
author name string
Cassandra J Vandenberg
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
language of work or name
English
0 references
publication date
11 November 2008
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
number of pages
6
1 reference
based on heuristic
inferred from page(s)
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
105
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
46
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
17961-17966
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
cites work
ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor
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Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.
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Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.
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29 September 2017
'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
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Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
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miR-15 and miR-16 induce apoptosis by targeting BCL2
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Myc pathways provoking cell suicide and cancer
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Live or let die: the cell's response to p53
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29 September 2017
Burkitt's lymphoma: molecular pathogenesis and treatment
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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
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Adult Burkitt's and Burkitt-like non-Hodgkin's lymphoma--outcome for patients treated with high-dose therapy and autologous stem-cell transplantation in first remission or at relapse: results from the European Group for Blood and Marrow Transplantat
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PubMed Central
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29 September 2017
Progenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survival
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PubMed Central
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29 September 2017
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
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PubMed Central
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The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
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PubMed Central
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27 June 2018
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4 September 2018
Molecular diagnosis of Burkitt's lymphoma
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PubMed Central
reference URL
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4 September 2018
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0809957105
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21 January 2018
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582212
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4 September 2018
Genetic analysis of chemoresistance in primary murine lymphomas.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582212
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4 September 2018
Bcl-2 mediates chemoresistance in matched pairs of primary E(mu)-myc lymphomas in vivo
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19004807
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antiapoptotic BCL-2 is required for maintenance of a model leukemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19004807
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19004807
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0809957105
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ADS bibcode
2008PNAS..10517961M
0 references
PMCID
2582212
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed ID
19004807
1 reference
stated in
Europe PubMed Central
PMCID
2582212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19004807%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
23469249
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